Selected Scientific Publications [1999 - 2017] Papers | Books | Home

Within the following list all articles are linked to theabstract service (IF: impact factor). Due to the copyright laws we are not allowed to link directly to the PDF-documents. However, via your university-network you might be eligible to download these files via PubMed and the appropriate publisher-links. Furthermore, you may search PubMed directly:

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Mixed Reality in visceral surgery – development of a suitable workflow and evaluation of intraoperative use-cases

I.M. Sauer, M. Queisner, P. Tang, S. Moosburner, O. Hoepfner, R. Horner, R. Lohmann, J. Pratschke

  Annals of Surgery, 2017 [in press] (IF: 8.980**)

The magnetic field of magnetic resonance imaging systems does not affect cells labeled with micrometer-sized iron oxide particles

M. Kluge, A. Leder, K.H. Hillebrandt, B. Struecker, D. Geisel, T. Denecke, R.D. Major, A. Reutzel-Selke, P. Tang, S. Lippert, Ch. Schmidt, J. Pratschke, I.M. Sauer, N. Raschzok

  Tissue Engineering Part C Methods, 2017 [Epub ahead of print] (IF: 3.485**)

Isolation, characterization and cold storage of cells isolated from diseased explanted livers

E. Belaschk, S. Rohn, R. Mukiibi, A. Reutzel-Selke, P. Tang, B. Sawitzki, J. Pratschke, I.M. Sauer, M.T. Mogl

  International Journal of Artificial Organs, 2017 [Epub ahead of print] (IF: 1.169**)

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans

H. Napierala, K. Hillebrandt, N. Haep, P. Tang, M. Tintemann, J. Gassner, M. Noesser, H. Everwien, N. Seiffert, M. Kluge, E. Teegen, D. Polenz, S. Lippert, D. Geisel, A. Reutzel-Selke, N. Raschzok, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker

  Nature Scientific Reports, 2017; 7:41777 | OPEN ACCESS (IF: 4.259**)

The value of microparticles in detecting acute rejection episodes after liver transplantation

M.H. Morgul, K. Splith, C. Leonhardt, N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, A. Andreou, C. Atanasov, C. Benzing, F. Krenzien, H.M. Hau, P. Felgendreff, S. Klunk, J. Pratschke, I.M. Sauer, M. Schmelzle

  Biomarkers, 2017 [Epub ahead of print] (IF: 2.006**)

Bovine serum albumine-glutaraldehyde sealed fish-mouth closure of the pancreatic remnant during distal pancreatectomy

F. Klein, I.M. Sauer, J. Pratschke, M. Bahra

  HPB Surgery, 2017 ;2017: 9747421 | OPEN ACCESS

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism

C. von Loeffelholz, S. Lieske, F. Neuschäfer-Rube, D.M. Willmes, N. Raschzok , I.M. Sauer, J. König, M. Fromm, P. Horn, A. Chatzigeorgiou, A. Pathe-Neuschäfer-Rube, J. Jordan, A.F. Pfeiffer, C. Mingrone, S.R. Bornstein, P. Stroehle, C. Harms, F.T. Wunderlich, S.L. Helfand , M. Bernier, R. de Cabo, G.I. Shulman, T. Chavakis, G.P. Püschel, A.L. Birkenfeld

  Hepatology, 2017 [Epub ahead of print] (IF: 13.246**)

Bile: miRNA pattern and protein based biomarkers may predict acute cellular rejection after liver transplantation

R.B. Schmuck, A. Reutzel-Selke, N. Raschzok, M.H. Morgul, B. Struecker, S. Lippert, C. de Carvalho Fischer, M. Schmelzle, S. Boas-Knoop, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer

  Biomarkers, 2017; 22(1): 19-27 (IF: 2.006**)

Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection

G. Duwe, S. Knitter, S. Pesthy, A.S. Beierle, M. Bahra, M. Schmelzle, R.B. Schmuck, P. Lohneis, N. Raschzok, R. Öllinger, M. Sinn, B. Struecker, I.M. Sauer, J. Pratschke, A. Andreou

  European Journal of Surgical Oncolology, 2017 [Epub ahead of print] (IF: 3.184**)

New technique for obesity surgery: internal gastric plication technique using intragastric single-port (IGS-IGP) in an experimental model

V. Müller, P. Fikatas, S. Gül, M. Noesser, K.T. Fuehrer, I. Sauer, J. Pratschke, R. Zorron

  Arquivos Brasileiros de Cirurgia Digestiva, 2017; 30(1): 60-64

Routine radiologic contrast agent examination after gastrectomy for gastric cancer is not useful

B. Struecker, S. Chopra, A.C. Heilmann, J. Spenke, C. Denecke, I.M. Sauer, M. Bahra, J. Pratschke, A. Andreou, M. Biebl

  Journal of Gastrointestinal Surgery, 2017; 21(5): 801-806 (IF: 2.963**)

Evolution of graft morphology and function after recellularization of decellularized rat livers

A. Butter, K. Aliyev, K.-H. Hillebrandt, N. Raschzok, M. Kluge, N. Seiffert, P. Tang, H. Napierala, M.I. Ashraf, A. Reutzel-Selke, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker

  Journal of Tissue Engineering and Regenerative Medicine, 2016 [Epub ahead of print] (IF: 3.989)

The impact of tumor cell proliferation on occult micrometastases, tumor recurrence and patient outcome following resection for liver malignancies

A. Andreou, M. Schmelzle, I.M. Sauer, M. Bahra, J. Pratschke

  Zentralblatt für Chirurgie, 2016; 141(4): 375-382 (IF: 0.405)

Computed tomography-based survey of the vascular anatomy of the juvenile Göttingen minipig

J. Siefert, K.H. Hillebrandt, M. Kluge, D. Geisel, P. Podrabsky, T. Denecke, M. Nösser, J. Gassner, A. Reutzel-Selke, B. Strücker, M.H. Morgul, S. Guel-Klein, J.K. Unger, A. Reske, J. Pratschke, I.M. Sauer, N. Raschzok

  Laboratory Animals, 2016 [Epub ahead of print]

Hepatocyte isolation after laparoscopic liver resection

R. Horner*, M. Kluge*, R.M. Major, A. Reutzel-Selke, J. Gassner, M. Nösser, B. Strücker, M.H. Morgül, J. Pratschke, I.M. Sauer, N. Raschzok

  Tissue Engineering – Part C Methods, 2016 [Epub ahead of print] (IF: 3.485)

Allogeneic liver transplantation and subsequent syngeneic hepatocyte transplantation in a rat model – proof of concept for in vivo tissue engineering

S. Rohn, J. Schroeder, H. Riedel, D. Polenz, K. Stanko, A. Reutzel-Selke, P. Tang, L. Brusendorf, N. Raschzok, P. Neuhaus, J. Pratschke, B. Sawitzki, I.M. Sauer, M.T. Mogl

  Cells Tissues Organs, 2016 [Epub ahead of print] (IF: 0.776)

microRNA signatures in peripheral blood fail to detect acute cellular rejection after liver transplantation

N. Raschzok, A. Reutzel-Selke, R. Schmuck, L. Tannus, M. Morgul, C. Dietel, A. Leder, B. Struecker, S. Lippert, H. Sallmon, M. Schmelzle, M. Bartels, S. Jonas, J. Pratschke, I.M. Sauer

  Biomarkers, 2016; 21:8, 699-707 (IF: 2.006)

Single Pass Albumin Dialysis (SPAD) – A dose finding study to define optimal albumin concentration and dialysate flow

R.B. Schmuck, G.-H. Nawrot, P. Fikatas, A. Reutzel-Selke, J. Pratschke, I.M. Sauer

  Artificial Organs, 2016 [Epub ahead of print] (IF: 2.403)

Human hepatocyte isolation: Does portal vein embolization affect the outcome?

M. Kluge, A. Reutzel-Selke, H. Napierala, K.H. Hillebrandt, R.D. Major, B. Struecker, A. Leder, J. Siefert, P. Tang, S. Lippert, D. Seehofer, J. Pratschke, I.M. Sauer, N. Raschzok

  Tissue Engineering – Part C Methods, 2016; 22(1): 38-48 (IF: 3.485)

Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver

C. von Loeffelholz, S. Döcke, J.F. Lock, S. Lieske, P. Horn, J. Kriebel, S. Wahl, P. Singmann, T. de Las Heras Gala, H. Grallert, N. Raschzok, I.M. Sauer, R. Heller, G. Jahreis, R.A. Claus, M. Bauer, M. Stockmann, A.L. Birkenfeld, A.F. Pfeiffer

  Hepatology Research, 2016, doi: 10.1111/hepr.12825. [Epub ahead of print] (IF: 2.602)

Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue – A statistical model based on stepwise penalized logistic regression

M.H. Morgul, S. Klunk, Z. Anastasiadou, U. Gauger, C. Dietel, A. Reutzel-Selke, P. Felgendref, H.M. Hau, H.M. Tautenhahn, R.B. Schmuck, N. Raschzok, I.M. Sauer, M. Bartels

  Experimental and Molecular Pathology, 2016; 101(2): 165-171 (IF: 2.423)

Predictive factors for extrahepatic recurrence of hepatocellular carcinoma following liver transplantation

A. Andreou, M. Bahra, M. Schmelzle, R. Öllinger, R. Sucher, I.M. Sauer, S. Guel-Klein, B. Struecker, D. Eurich, F. Klein, A. Pascher, J. Pratschke, D. Seehofer

  Clinical Transplantation, 2016; 30(7): 819-827 (IF: 1.865)

Risk factors for bile leakage after hepatectomy

B. Struecker, A. Andreou, I.M. Sauer, J. Pratschke, D. Seehofer

  Hepatobiliary & Pancreatic Diseases International, 2016; 15(1): 12-13 (IF: 1.649)

Implantation of a tissue engineered Neo Bile Duct in domestic pigs

B. Struecker, K. Hillebrandt, N. Raschzok, K. Jöhrens, A. Butter, P. Tang, A. Andreou, H. Napierala, D. Polenz, A. Reutzel-Selke, T. Denecke, J. Pratschke, I.M Sauer

  European Surgical Research, 2016; 56: 61-75 (IF: 1.382)

The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C

N. Raschzok, E. Schott, A. Reutzel-Selke, I. Damrah, S. Gül-Klein, B. Strücker, I.M. Sauer, J. Pratschke, D. Eurich, M. Stockmann

  Transplant Infectious Disease, 2016; doi: 10.1111/tid.12606. [Epub ahead of print] (IF: 1.719)

The Impact of Obesity on Outcomes Following Resection for Gastric Cancer

B. Struecker, M. Biebl, M. Dadras, S. Chopra, C. Denecke, J. Spenke, A.C. Heilmann, M. Bahra, I.M. Sauer, J. Pratschke, A. Andreou

  Digestive Surgery, 2016; 34(2): 133-141. [Epub ahead of print] (IF: 1.664)

Acute graft dysfunction 17 years after liver transplant: A challenging clinical and histologic manifestation of hepatitis E

K.H. Hillebrandt, R. Arsenic, J. Hofmann, D. Eurich, S. Gül, B. Strücker, I.M. Sauer, J. Pratschke, M. Stockmann, N. Raschzok

  Experimental and Clinical Transplantation 2016 Jun 15. doi: 10.6002/ect.2015.0343. [Epub ahead of print] (IF: 0.535)

Anastomotic leak predicts diminished long-term survival after resection for gastric and esophageal cancer

A. Andreou, M. Biebl, M. Dadras, B. Struecker, I.M. Sauer, P.C. Thuss-Patience, S. Chopra, P. Fikatas, M. Bahra, D. Seehofer, J. Pratschke, S.C. Schmidt

  Surgery 2016;160(1): 191-203 (IF: 3.904)

microRNAs in liver tissue engineering – new promises for failing organs

N. Raschzok, H. Sallmon, J. Pratschke, I.M. Sauer

  Advanced Drug Delivery Reviews, 2015; 88: 67-77 (IF: 15.606)

Procedure for Decellularization of Rat Livers in an Oscillating-pressure Perfusion Device

K. Hillebrandt, D. Polenz, A. Butter, P. Tang, A. Reutzel-Selke, A. Andreou, H. Napierala, N. Raschzok, J. Pratschke, I.M. Sauer, B. Struecker

  Journal of Visualized Experiments, 2015;(102). doi: 10.3791/53029 (IF: 1.113)

CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation

N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, M.H. Morgul, U. Gauger,K.A. Prabowo, L.-M. Tannus, A. Leder, B. Struecker, S. Boas-Knoop, M. Bartels, S. Jonas, Ch. Lojewski, G. Puhl, D. Seehofer, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer

  Liver Transplantation, 2015; 21(9): 1195-1207 (IF: 3.951)

Tissue Engineered Grafts – 160 Years After R. Virchow's Omnis Cellula e Cellula

I.M. Sauer

  Transplantation, 2015; 99(3): 462-463 (IF: 3.690)

Micron-sized iron oxide-containing particles for microRNA-targeted manipulation and MRI-based tracking of transplanted cells

A. Leder*, N. Raschzok*, C. Schmidt, D. Arabacioglu, A. Butter, S. Kolano, L.S. de Sousa Lisboa, W. Werner, D. Polenz, A. Reutzel-Selke, J. Pratschke, I.M. Sauer

  Biomaterials, 2015; 51: 129-137 (IF: 8.387)

Tumor DNA index and α-fetoprotein level define outcome following liver transplantation for advanced hepatocellular carcinoma

A. Andreou, M. Bahra, S. Guel, B. Struecker, I.M. Sauer, F. Klein, A. Pascher, J. Pratschke, D. Seehofer

  European Surgical Research 2015; 55(4): 302-318

Liver support strategies: cutting-edge technologies

B. Struecker, N. Raschzok, I.M. Sauer

  Nature Reviews – Gastroenterology and Hepatology, 2014; 11(3): 166-176 (IF: 12.610)

Hedgehog pathway as a potential treatment target in human cholangiocarcinoma

D. Riedlinger, M. Bahra, S. Boas-Knoop, S. Lippert, M. Bradtmöller, K. Guse, D. Seehofer, R. Bova, I.M. Sauer, P. Neuhaus, A. Koch, C. Kamphues

  Journal of Hepato-Biliary-Pancreatic Sciences, 2014; 21(8): 607-615 (IF: 2.994)

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions

B. Struecker, A. Butter, K. Hillebrandt, D. Polenz , A. Reutzel-Selke, P. Tang, S. Lippert, A. Leder, S. Rohn, D. Geisel, T. Denecke, K. Aliyev, K. Jöhrens, N. Raschzok, P. Neuhaus, J. Pratschke, I.M. Sauer

  Journal of Tissue Engineering and Regenerative Medicine, 2014 [Epub ahead of print] (IF: 5.199)

Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process

B. Struecker, K. Hillebrandt, R. Voitl, A. Butter, R.B. Schmuck, A. Reutzel-Selke, D. Geisel, K. Joehrens, P.A. Pickerodt, N. Raschzok, G. Puhl, P. Neuhaus, J. Pratschke, I.M. Sauer

  Tissue Engineering, Part C: Methods, 2015 21(3): 303-313 (IF: 4.254)

Independent Effects of Sham Laparotomy and Anesthesia on Hepatic microRNA Expression in Rats

W. Werner, H. Sallmon, A. Leder, S. Lippert, A. Reutzel-Selke, M.H. Morgül, S. Jonas, S. Dame, P. Neuhaus, J. Iacomini, S.G. Tullius, I.M. Sauer, N. Raschzok

  BMC Research Notes, 2014; 7:702

Functionalizable silica-based micron-sized iron oxide particles for cellular Magnetic Resonance Imaging

N. Raschzok, C.M. Langer, Ch. Schmidt, K.H. Lerche, N. Billecke, K. Nehls, N.B. Schlüter, A. Leder, S. Rohn, M.T. Mogl, L. Lüdemann, L. Stelter, U.K. Teichgräber, P. Neuhaus, I.M. Sauer


Cell Transplantation, 2013; 22(11): 1959-1570 (IF: 3.57)


APACHE III score is superior to King's College Hospital criteria, MELD score and APACHE II score to predict outcomes after liver transplantation for acute liver failure

P. Fikatas, J.E. Lee, I.M. Sauer, S.C. Schmidt, D. Seehofer, G. Puhl, O. Guckelberger

  Transplantation Proceedings, 2013; 45: 2295-2301 (IF: 0.984)

Survival without biliary complications after liver transplant for primary sclerosing cholangitis

M.T. Mogl, K. Albert, A. Pascher, I. Sauer, G. Puhl, S. Gül, C. Schönemann, P. Neuhaus, O. Guckelberger

  Experimental and Clinical Transplantation, 2013; 11(6): 510-521 (IF: 0.798)

Elevated hepatic chemerin gene expression in progressed human non-alcoholic fatty liver disease

S. Döcke, J.F. Lock, A.L. Birkenfeld, S. Hoppe, S. Lieske, A. Rieger, N. Raschzok, I.M. Sauer, S. Florian, M.A. Osterhoff, R. Heller, K. Herrmann, S. Lindenmüller, P. Horn, M. Bauer, M.O. Weickert, P. Neuhaus, M. Stockmann, M. Möhlig, A.Fh. Pfeiffer C. von Loeffelholz

  European Journal of Endocrinology, 2013; 169(5): 547-557 (IF: 3.686)

Evaluation of Arginine deiminase treatment in melanoma xenografts using 18F-FLT PET

L. Stelter, S. Fuchs, A. Jungbluth, G. Ritter, V. Longo, P. Zanzonico, N. Raschzok, I. Sauer, J. Bomalaski, S. Larson

  Molecular Imaging & Biology 2013; 15: 768-775 (IF: 2.869)

Noninvasive monitoring of liver cell transplantation

N. Raschzok, H.M. Morgül, L. Stelter, I.M. Sauer

Imaging in Medicine, 2013; 5: 47-61

Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices

G. Tong, S. Endersfelder, L.M. Rosenthal, S. Wollersheim, I.M. Sauer, C. Bührer, F. Berger, K.R. Schmitt

  Brain Research, 2013; 1504:74-84 (IF: 2.828)

Identification of a novel human polyomavirus in organs of the gastrointestinal tract

S. Korup, J. Rietscher, S. Calvignac-Spencer, F. Trusch, J. Hofmann, U. Moens, I. Sauer, S. Voigt, R. Schmuck, B. Ehlers

  PLOS ONE, 2013; 8(3): e58021 (IF: 3.534)

Feasibility of fast dynamic MRI for non-invasive monitoring during ectopic liver cell transplantation to the spleen in a porcine model

N. Raschzok, J. Pinkernelle, N. Billecke, K. Nehls, M. Powerski, I.M. Sauer, U. Teichgraber

American Journal of Roentgenology, 2012; 198: 1417-1423 (IF: 2.897)


A novel cannulation technique for isolation of human hepatocytes from explanted, diseased whole livers

D.C. Kehr, N. Raschzok, I.M. Sauer

Transplantation Proceedings, 2012; 44: 999-1001 (IF: 0.952)

Liver regeneration after partial hepatectomy: inconsistent results of expression screenings for human, mouse, and rat miRNAs

N. Raschzok, H. Sallmon, C. Dame, I.M. Sauer

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2012; 302: G470-471 (IF: 3.649)


An operational concept for long-term cinemicrography of cells in mono- and co-culture under highly controlled conditions - the SlideObserver

N. Billecke, N. Raschzok, S. Rohn, M.H. Morgul, R. Schwartlander, M. Mogl, S. Wollersheim, K.R. Schmitt*, I.M. Sauer*

Journal of Biotechnology, 2012; 159: 83-89 (IF: 3.183)

Improvement of the cold storage of isolated human hepatocytes

G. Pless, I.M. Sauer, U. Rauen

Cell Transplantation, 2012; 21: 23-27 (IF: 4.422)

Temporal expression profiles indicate a primary function for microRNA during the peak of DNA replication after rat partial hepatectomy

N. Raschzok, W. Werner, H. Sallmon, N. Billecke, C. Dame, P. Neuhaus, I.M. Sauer

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 2011; 300: 1363-1372 (IF: 3.336)

Labelling of primary human hepatocytes with micron-sized iron oxide particles in suspension culture suitable for large-scale preparation

N.N. Kammer, N. Billecke, M.H. Morgul, M.K. Adonopoulou, M. Mogl, M.D. Huang, S. Florek, K.R.L. Schmitt, N. Raschzok, I.M. Sauer

Artificial Organs, 2011; 35: 91-100 (IF: 2.0)

CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells

G. Rago, C.M. Langer, C. Brackman, J.P. Day, K.F. Domke, N. Raschzok, C. Schmidt, I.M. Sauer, A. Enejder, M.T. Mogl, M. Bonn

Biomedical Optics Express, 2011; 2: 2470-2483 (IF: 2.333)

The APACHE III score as preoperative indicator of patient outcome in liver transplantation after fulminant hepatic failure

P. Fikatas, F. Ulrich, J.E. Lee, I.M. Sauer, S. Chopra, S.C. Schmidt, A. Pascher, J. Pratschke

Annals of Transplantation, 2011; 16: 18-25 (IF: 2.02)

In vitro evaluation of magnetic resonance imaging contrast agents for labeling human liver cells: implications for clinical translation

N. Raschzok, D.A. Muecke, M.K. Adonopoulou, N. Billecke, W. Werner, N.N. Kammer, A. Zielinski, P.A. Behringer, F. Ringel, M.D. Huang, P. Neuhaus, U. Teichgräber, I.M. Sauer

Molecular Imaging & Biology, 2011; 13: 613-622 (IF: 3.844)


Continuous veno-venous single-pass albumin hemodiafiltration in children with acute liver failure

H. Ringe, V. Varnholt, M. Zimmering, W. Luck, A. Gratopp, K. König, S. Reich, I.M. Sauer, G. Gaedicke, U. Querfeld

Pediatric Critical Care Medicine, 2011; 12: 257-264 (IF: 3.129)

Monitoring of liver cell transplantation in a preclinical swine model using Magnetic Resonance Imaging

N. Raschzok, U. Teichgräber, N. Billecke, A. Zielinski, K. Steinz, N.N. Kammer, M.H. Morgul, S. Schmeisser, M.K. Adonopoulou, L. Morawietz, B. Hiebl, R. Schwartlander, W. Rüdinger, B. Hamm, P. Neuhaus, I.M. Sauer

Cell Medicine 1(3): 123-135 

Modification of aminosilanized superparamagnetic nanoparticles: feasibility of multimodal detection using 3T MRI, small animal PET, and fluorescence imaging

L. Stelter, J. Pinkernelle, R. Michel, R. Schwartlander, N. Raschzok, M.H. Morgul, M. Koch, T. Denecke, H. Amthauer, J. Ruf, A. Jordan, B. Hamm, I.M. Sauer, U. Teichgraber

Molecular Imaging & Biology, 2010; 12: 25-34 (IF: 3.139)

Aging of the liver graft and functional quality in the absence of recurrent disease: a 10 year histological follow-up

M. Schmeding, I.M. Sauer, K. Hartwig, T. Theruvath, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann

Annals of Transplantation, 2010; 15: 5-13 (IF: 0.975)

Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro 

A. Diestel, S. Troeller, N. Billecke, I.M. Sauer, F. Berger, K.R.L. Schmitt

European Journal of Neuroscience, 2010; 31: 779-787

Quantification of Cell Labelling with Micron-Sized Iron Oxide Particles Using Continuum Source Atomic Absorption Spectrometry

N. Raschzok, N. Billecke, N.N. Kammer, M.H. Morgul, M.K. Adonopoulou, I.M. Sauer, S. Florek, H. Becker-Ross, M.-D. Huang

Tissue Engineering - Part C, Methods, 2009; 15: 681-686 (IF: 4.582)

Sonographically guided placement of intravenous catheters in minipigs

J. Pinkernelle, N. Raschzok, U. Teichgräber

Lab Anim (NY). 2009; 38(7): 241-245

Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes

T. Deurholt, N.P. van Til, A.A. Chhatta, L. ten Bloemendaal, R. Schwartlander, C. Payne, J.N. Plevris, I.M. Sauer, R.A. Chamuleau, R.P. Elferink, J. Seppen, R. Hoekstra

BMC Biotechnology, 2009; 9: 89-103 (IF: 2.723)

Aspergillus spondylodiscitis after multivisceral transplantation

U.A. Gerlach, S. Kohler, I.M. Sauer, D. Joerres, F. Kandziora, P. Neuhaus, J. Pratschke, A. Pascher

Annals of Transplantion, 2009; 14: 52-57 (IF: 0.969)

Tacrolimus and methylprednisolone prevent hypothermia induced endothelial dysfunction

A. Diestel, N. Billecke, J. Roessler, B. Schmitt, S. Troeller, R. Schwartlander, F. Berger, I.M. Sauer*, K.R.L. Schmitt*

Journal of Heart and Lung Transplantation, 2009, 28: 718-724 (IF: 3.514)

Successful treatment of invasive sphenoidal, pulmonary and intracerebral aspergillosis after multivisceral transplantation

S. Kohler, U. Gerlach, O. Guckelberger, I.M. Sauer, D. Jörres, P. Neuhaus, J. Pratschke, A. Pascher

Transplantation International, 2009, 22: 589-591 (IF: 3.254)

Imaging of Primary Human Hepatocytes Using Micron-Sized Iron Oxide Particles and Clinical Magnetic Resonance Tomography

N. Raschzok*, M.H. Morgul*, J. Pinkernelle, F.W.R. Vondran, N. Billecke, N.N. Kammer, G. Pless, M.K. Adonopoulou, C. Leist, L. Stelter, U. Teichgraber, R. Schwartlander, I.M. Sauer

Journal of Cellular and Molecular Medicine 2008, 12: 1384-1394 (IF: 5.114)

Tracking of primary human hepatocytes with clinical MRI – initial results with Tat-peptide modified superparamagnetic iron oxide particles

M.H. Morgul*, N.Raschzok*, R. Schwartlander, F.W.R. Vondran, R. Michel, L. Stelter, J. Pinkernelle, A. Jordan, U. Teichgraber, I.M. Sauer

International Journal of Artificial Organs 2008, 31: 252-257 (IF: 1.299)

Isolation of primary human hepatocytes after partial hepatectomy – Criteria for identification of the most promising liver specimen

F.W.R.Vondran, E. Katenz, R. Schwartlander, M.H. Morgul, N. Raschzok, X.B.Gong, X.D. Cheng, D. Kehr, I.M. Sauer

Artificial Organs 2008, 32: 205-213 (IF: 2.131)

Graft versus host disease after liver transplantation - a single center experience and review of literature

S. Kohler, A. Pascher, G. Junge, I.M. Sauer, M. Nagy, C. Schönemann, M. Koch, U. Neumann, J. Pratschke, P. Neuhaus

Transplantation International 2008, 21: 441-451 (IF: 3.115)

Heterotopic ileal pancreas with lipoma and coexisting fibromatosis associated with a rare case of gastrointestinal bleeding. A case report and review of the literature.

P. Fikatas, I.M. Sauer, M. Mogl, C. Menenakos, A. Luegering, G. Schumacher, J. Langrehr, P. Neuhaus

Journal of the Pancreas 2008, 9: 640-643

Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: Technical aspects

A. Spinelli, G. Schumacher, C. Benckert, I.M. Sauer, M. Schmeding, M. Glanemann, U.P. Neumann, S. Jonas, P. Neuhaus

European Journal of Surgical Oncololgy 2008, 34: 831-835

Continuously microscopically observed and process controlled cell culture within the SlideReactor – proof of a new concept for cell characterization

R. Schwartlander, J. Schmid, B. Brandenburg, E. Katenz, F.W.R. Vondran, G. Pless, X. Cheng, A. Pascher, P. Neuhaus, I.M. Sauer

Tissue Engineering 2007, 13: 187-196 (IF: 4.409)

Somatostatin receptor subtype-2-deficient mice with diet-induced obestiy have hyperglycemia, non-fasting hyperglucagonemia and decreased hepatic glycogen deposition

V. Singh, C. Grotzinger, K.W. Nowak, S. Zacharias, E. Goncz, G. Pless, I.M. Sauer, I. Eichhorn, B. Pfeiffer-Guglielmi, B. Hamprecht, B. Wiedenmann, U. Plockinger, M.Z. Strowski

Endocrinology 2007, 148: 3887-3899 (IF: 5.045)

Artificial and Bioartificial Liver Support

G. Pless

Organogenesis 2007, 3: 20-24

Cryopreservation of primary human hepatocytes – the benefit of trehalose as an additional cryoprotective agent

E. Katenz, F.W.R. Vondran, R. Schwartlander, G. Pless, X. Gong, X. Cheng, P. Neuhaus, I. M. Sauer

Liver Transplantation 2007, 13: 38-45 (IF: 3.751)

Influence of basiliximab induction therapy on long term outcome after liver transplantation, a prospectively randomised trial

M. Schmeding, I.M. Sauer, A. Kiessling, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann

Annals of Transplantation 2007, 12: 15-21

First in vitro comparison of two bioartificial liver support systems: MELS CellModule and AMC-BAL

P.P.C. Poyck, G. Pless, R. Hoekstra, S. Roth, A.C.W.A. van Wijk, R. Schwartlander, T.M. van Gulik, I.M. Sauer, R.A.F.M. Chamuleau

International Journal of Artificial Organs 2007, 30: 183-191 (IF: 1.277)

Evaluation of primary human liver cells in bioreactor cultures for extracorporeal liver support on the basis of urea production

G. Pless, I. Steffen, K. Zeilinger, I.M. Sauer, E. Katenz, D.C. Kehr, S. Roth, T. Mieder, R. Schwartlander, Ch. Müller, B. Wegner, M. S. Hout, P. Neuhaus, J.C. Gerlach

Artificial Organs 2006, 30: 686-694 (IF: 1.903)

Cell-free artificial liver support

I.M. Sauer, U. Baurmeister

Therapeutic Apheresis and Dialysis 2006, 10: 105-107 (IF: 1.177)

Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature

A. Spinelli, G. Schumacher, A. Pascher, E. Lopez-Hanninen, H. Al-Abadi, C. Benckert, I.M. Sauer, J. Pratschke, U.P. Neumann, S. Jonas, J.M. Langrehr, P. Neuhaus

  World Journal of Gastroenterolology 2006, 12: 2293-2296

Novel system for efficient gene transfer into primary human hepatocytes via cell permeable HBV virus-like particle

B. Brandenburg, L. Stockl, C. Gutzeit, M. Roos, J. Lupberger, R. Schwartlander, H. Gelderblom, I.M. Sauer, P.H. Hofschneider, E. Hildt

Hepatology 2005, 42: 1300-1309 (IF: 9.792)

The SlideReactor - a simple hollow fiber based bioreactor suitable for light microscopy

I.M. Sauer, R. Schwartlander, J. Schmid, E. Efimova, F.W.R. Vondran, D. Kehr, G. Pless, A. Spinelli, B. Brandenburg, E. Hildt, and P. Neuhaus

Artificial Organs 2005, 29: 264-267 (IF: 1.946)

Clinical results of intestinal and multivisceral transplantation at the Charité, Berlin

A. Pascher, J. Klupp, R.J. Schulz, S. Kohler, G. Junge, I.M. Sauer, W. Veltzke-Schlieker, A. Adler, O. Guckelberger, N.C. Nussler, A. Dignass, J.M. Langrehr, P. Neuhaus

  Deutsche Med Wochenschrift 2005,130: 387-392 (IF: 0.653)

In vitro evaluation of the transportability of viable primary human liver cells originating from discarded donor organs in bioreactors

I.M. Sauer, R. Schwartlander, O. van der Jagt, I. Steffen, E. Efimova, G. Pless, D.C. Kehr, D. Kardassis, J.H. Fruhauf, J.C. Gerlach, P. Neuhaus

Artificial Organs 2005, 29: 141-151 (IF: 1.946)

“Blogs” and “Wikis” are valuable software tools for communication within research groups

I.M. Sauer, D. Bialek, E. Efimova, R. Schwartlander, G. Pless, P. Neuhaus

  Artificial Organs 2005, 29: 82-83 (IF: 1.946)

The European artificial organ scene: present status

R. Vanholder, J. de Cañizo, I.M. Sauer, B Stegmayr

Artificial Organs 2005, 29: 498-506 (IF: 1.946)

Bioartificial liver: current status

G. Pless, I.M. Sauer


Transplantation Proceedings 2005, 37:3893-3895 (IF: 0.799)


In vitro comparison of the Molecular Adsorbent Recirculation System (MARS) and Single Pass Albumin Dialysis (SPAD)

I.M. Sauer, M. Goetz, I. Steffen, G. Walter, D.C. Kehr, R. Schwartlander, Y.J. Hwang, A. Pascher, J.C. Gerlach, P. Neuhaus

Hepatology 2004, 39: 1408-1414 (IF: 10.416)


Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines

E.A. Efimova, M. Glanemann, L. Liu, G. Schumacher, U. Settmacher, S. Jonas, J.M. Langrehr, P. Neuhaus, A.K.Nussler

European Surgical Research 2004, 36: 300-307 (IF: 0.75)

Time course of primary liver cell reaorganization in three-dimensional high-density bioreactors for extracorporeal liver support: An immunohistochemical and ultrastructural study

K. Zeilinger, G. Holland, I.M. Sauer, E. Efimova, D. Kardassis, N. Obermayer, M. Liu, P. Neuhaus, J.C. Gerlach

Tissue Engineering 2004, 10: 1113-1124 (IF: 3.143)

Bilirubin-adsorption in 23 critically ill patients with liver failure

R. Senf, R. Klingel, S. Kurz, S. Tullius, I.M. Sauer, U. Frei, R. Schindler


International Journal of Artificial Organs 2004, 27: 717-722 (IF: 1.065)


The use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors – a morphological study

J.C. Gerlach, K. Mutig, I.M. Sauer, P. Schrade, E. Efimova, T. Mieder, G. Nauman, A. Grünwald, G. Pleß, A. Mas, S. Bachmann, P. Neuhaus, K. Zeilinger

  Transplantation 2003, 76: 781-786 (IF: 3.608)

Extracorporeal Liver Support based on Primary Human Liver Cells and Albumin Dialysis – Treatment of a Patient with Primary Graft Non-Function

I.M. Sauer, K. Zeilinger, G. Pless, D. Kardassis, T. Theruvath, A. Pascher, M. Goetz, P. Neuhaus, J. C. Gerlach
  Journal of Hepatology 2003, 39: 649-653 (IF: 5.283)

Porcine endogenous retroviruses (PERVs): No infection in patients treated with a bioreactor based on porcine liver cells

M. Irgang, I.M. Sauer, A. Karlas, K. Zeilinger, J.C. Gerlach, R. Kurth, P. Neuhaus, J. Denner
  Journal of Clinical Virology 2003, 28: 141-154 (IF: 2.020)

Clinical extracorporeal hybrid liver support – phase I study with primary porcine liver cells

I.M. Sauer, D. Kardassis, K. Zeillinger, A. Pascher, A. Gruenwald, G. Pless, M. Irgang, M. Kraemer, G. Puhl, J. Frank, A.R. Müller, Th. Steinmüller, J. Denner, P. Neuhaus, J. C. Gerlach
  Xenotransplantation 2003, 10: 460-469 (IF: 2.437)

Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation

A. Pascher, C. Radke, A. Dignass, R.J. Schulz, W. Veltzke-Schlieker, A. Adler, I.M. Sauer, K. Platz, J. Klupp, H.D. Volk, P. Neuhaus, A.R. Mueller
  Transplantation 2003, 76: 615-618 (IF: 3.608)

Late Graft Loss After Intestinal Transplantation in an Adult Patient as a Result of Necrotizing Enterocolitis

A. Pascher, C. Radke, A. Dignass, R. Schulz, I.M. Sauer, K. Platz, J. Klupp, P. Neuhaus, A. Mueller
  American Journal of Transplantation 2003, 3: 1033-1035 (IF: 5.678)

Recovery of Preservation Injured Primary Human Hepatocytes and Nonparenchymal Cells to Tissue-Like Structures in Large-Scale Bioreactors for Liver Support: An Initial Transmission Electron Microscopy Study

J.C. Gerlach, K. Zeilinger, A. Grebe, G. Puhl, G. Pless, I.M. Sauer, A. Grunwald, N. Schnoy, C. Muller, P. Neuhaus
  Journal of Investigative Surgery 2003, 16: 83-92 (IF: 0.616)

Einsatz biologischer Leberunterstützungssysteme bei der Therapie des Leberversagens – Modular Extracorporeal Liver Support (MELS)

T.P. Theruvath, I.M. Sauer, D. Kardassis, N. Obermayer, A. Pascher, M. Goetz, A.R. Mueller, Th. Steinmueller, P. Neuhaus, J.C. Gerlach
  Verdauungskrankheiten 2003, 21: 32-40

Concept for modular extracorporeal liver support for the treatment of acute hepatic failure

I.M. Sauer, P. Neuhaus, J.C. Gerlach
  Journal of Metabolic Brain Disease 2002, 17: 477-484 (IF: 1.078)

Extracorporeal liver support: Porcine or human cell based systems?

J.C. Gerlach, K. Zeilinger, I.M. Sauer, T. Mieder, G. Naumann, A. Grünwald, G. Pless, G. Holland, A. Mas, J. Vienken, P. Neuhaus
  International Journal of Artificial Organs 2002, 25: 1013-1018 (IF: 1.192)

Primary human liver cells as source for modular extracorporeal liver support – a preliminary report

I.M. Sauer, K. Zeilinger, N. Obermayer, G. Pless, A. Pascher, T. Mieder, S. Roth, M. Goetz, D. Kardassis, A. Mas, P. Neuhaus, J.C. Gerlach
  International Journal of Artificial Organs 2002, 25: 1001-1005 (IF: 1.192)

Analysis of allogeneic versus xenogeneic auxiliary organ perfusion in liver failure reveals superior efficacy of human livers

 A. Pascher, I.M. Sauer, P. Neuhaus
  International Journal of Artificial Organs 2002, 25: 1006-1012 (IF: 1.192)

Three-dimensional Co-culture of Primary Human Liver Cells in Bioreactors for In Vitro Drug Studies: Effects of the Initial Cell Quality on the Long-term Maintenance of Hepatocyte-specific Functions.

K. Zeilinger K, I.M. Sauer, G. Pless, C. Strobel, J. Rudzitis, A. Wang, A.K. Nussler, A. Grebe, L. Mao, S.H. Auth, J. Unger, P. Neuhaus, J.C. Gerlach
  Alternatives to Laboratory Animals 2002; 30: 539-550 (IF: 2.022)

Modified surgical technique in clinical small bowel transplantation: donor and recipient management.

A. Mueller, A. Pascher, K. Platz, N. Nussler, R. Schulz,D. Horch,T. Melitz,I. M. Sauer, R. Eisele,U. Settmacher,A. Dignass,E. Lopez-Henninen,H. Weidemann,P. Neuhaus
  Transplantation Proceedings 2002; 34: 2265 (IF: 0.478)

Living-Donation Liver Transplantation for Hepatocellular Carcinoma: Time to Drop the Limitations?

Th. Steinmüller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Müller, U.Settmacher, P. Neuhaus
  Transplantation Proceedings 2002; 34: 2263-2264 (IF: 0.478)

Donor evaluation, donor risks, donor outcome, and donor quality of life in adult-to-adult living donor liver transplantation

A. Pascher, I.M. Sauer, M. Walter, E. Lopez-Haeninnen, T. Theruvath, A. Spinelli, R. Neuhaus, U. Settmacher, A. R. Mueller, Th. Steinmueller, P. Neuhaus
  Liver Transplantation 2002; 8: 829-837 (IF: 3.786)

A method to assess biochemical activity of liver cells during clinical application of extracorporeal liver support

A. Mundt, G. Puhl, A. Müller, I. Sauer, C. Müller, R. Richard, C. Fotopoulou, R. Doll, G. Gäblein, W. Höhn, R. Hofbauer, P. Neuhaus, J. Gerlach
  International Journal of Artificial Organs 2002; 25: 542-548 (IF: 1.192)

Modular Extracorporeal Liver Support (MELS)

I.M. Sauer, J.C. Gerlach
  Artificial Organs 2002; 26: 703-706 (IF: 0.926)

Extracorporeal Liver Perfusion as Hepatic Assist in Acute Liver Failure - A Review of World Experience

A. Pascher, I.M. Sauer, C. Hammer, J.C. Gerlach, P. Neuhaus
  Xenotransplantation 2002; 9: 309-324 (IF: 2.581)

[Right lobe living donor liver transplantation between adults]

T. Steinmuller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Muller, U. Settmacher , P. Neuhaus
  Deutsche Medizinische Wochenschrift 2002, 127: 1067-1071 (IF: 0.651)

Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.

K.P. Platz, A. Pascher, R.J. Schulz, N.C. Nussler, I.M. Sauer, U. Settmacher, R. Eisele, A. Dignass, E. Lopez-Henninen, P. Neuhaus, A.R. Mueller
  Transplantation Proceedings 2002, 34: 906-907 (IF: 0.478)

Monitoring of immunosuppression after clinical small bowel transplantation.

A. Pascher, I.M. Sauer, R.J. Schulz, K. Platz, T. Theruvath, A. Dignass, C. Radke, P. Neuhaus, A.R. Mueller
  Transplantation Proceedings 2002, 34: 931-933 (IF: 0.478)

Experimental evaluation of a cell module for hybrid liver support

J.C. Gerlach, M. Botsch, D. Kardassis, P. Lemmens, M. Schoen, J. Janke, G. Puhl, J. Unger, M. Kraemer, B. Busse, B. Boehmer, R. Belal, M. Ingenlath, M. Kosan, B. Kosan, J. Sueltmann, A. Patzold, S. Tietze, R. Roissant, C. Mueller, E. Moench, I.M. Sauer, P. Neuhaus
  International Journal of Artificial Organs 2001, 24: 793-798 (IF: 1.072)

Development of a hybrid liver support system

I.M. Sauer, N. Obermayer, D. Kardassis, T. Theruvath, J.C. Gerlach
  Annals of the New York Academy of Sciences 2001, 944: 308-119 (IF: 1.593)

Modular Extracorporeal Liver Support (MELS) bei Leberversagen

D. Kardassis, T.P. Theruvath, I.M. Sauer, J.C. Gerlach, P. Neuhaus.
  Journal für Anästhesie und Intensivbehandlung 2001, 3: 97-99

Split liver and living donation liver transplantation: the Berlin experience.

I.M. Sauer, A. Pascher, Th. Steinmueller, U. Settmacher, A.R. Müller, W.O. Bechstein, P. Neuhaus
  Transplantation Proceedings 2001; 33: 1459-1460 (IF: 0.568)


I.M. Sauer, A. Pascher, R. Pfitzmann, A.R. Mueller, P. Neuhaus
  Chirurgische Praxis 2000, 57: 411-427

TAH Ovalis - Development and in vitro testing of a new electromechanical energy converter for a total artificial heart

I.M. Sauer, J. Frank, A.Spiegelberg, E.S. Bücherl
  ASAIO Journal 2000; 46: 744-748 (IF: 1.152)

An unusual case of early pancreas graft loss.

I.M. Sauer, A. Kahl, A.R. Müller, P. Neuhaus, W.O. Bechstein
  Annals of Transplantation 1999; 4(2): 52-54

Proposal of a new electro-mechanical heart: TAH Serpentina

I.M. Sauer, J. Frank, E.S. Bücherl
  Artificial Organs 1999; 23: 290-291 (IF: 0.854)


* contributed equally, ** impact factors 2016



Book chapters


Preclinical swine models for monitoring of hepatocyte transplantation by MRI Hepatocyte Transplantation – Methods and Protocols (Editors: Stock, Christ)

N. Raschzok, U. Teichgräber, J. Pratschke, I.M. Sauer

Springer Verlag, 2017 (ISBN: 978-1-4939-6506-9)

Extracorporeal Liver Support, Liver-Cell Transplantation, and Bioengineered Substitutes. In: Textbook of Organ Transplantation (Editors: Kirk, Knechtle, Larsen, Pearson, Webber)

I.M. Sauer, N. Raschzok, P. Neuhaus

  Wiley-Blackwell, 2014 (ISBN: 978-1-118-87014-3)

Extracorporeal liver support. In: Management of acute kidney problems (Editors: Ronco, Kellum, Jörres)

I.M. Sauer

Springer Verlag, 2009 (ISBN: 978-3-540-69413-7)

Akutes Nierenversagen bei Intensivpatienten: Extrakorporale Leberersatzverfahren (Editor: Jörres)

G. Pless, I.M. Sauer

Deutscher Ärzte Verlag, 2009 (ISBN 978-3-7691-0477-6)

Hybride Organe: Künstliche und zellbasierte Leberunterstützungssysteme. In: Chirurgische Forschung (Editors: Krukemeyer, Spiegel)

I.M. Sauer, P. Neuhaus

Georg Thieme Verlag, 2006: 366-378 (ISBN: 3-13-133661-7)

Modular Extracorporeal Liver Support. In: Artificial Liver Support (Editors: Henne-Bruns, Buttenschön, Fuchs, Lohse)
Falk-Symposium, Vol. 145, 2005

I.M. Sauer

Springer Verlag, 2005: 53-60 (ISBN: 1-4020-3239-0)

Extrakorporale Leberunterstützungssysteme. In: Aktuelle Aspekte der Lebertransplantation
(Editors: Neuhaus, Pfitzmann)

G. Puhl, I.M. Sauer

UniMed-Verlag, 2. Edition, 2005: 60-69 (ISBN 3-89599-774-9)

Liver Transplantation. In: Surgical treatment. Evidence-based and problem-oriented (Editor: Mannick)

I.M. Sauer, W.O. Bechstein, P. Neuhaus

Zuckschwerdt Verlag, München, Bern, Wien, New York: 298-305 (ISBN: 3-88603-714-2)

Hepatozyten-Tissue Engineering und Bioreaktoren für hybride Leberunterstützungssysteme (Editor: Encke)

I.M. Sauer, J.C. Gerlach, P. Neuhaus

Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769

Development of a Hybrid Liver Support System.
Bioartificial Organs III: Tissue Sourcing, Immunoisolation, and Clinical Trials (Editors: Hunkeler, Cherrington, Prokop, and Rajotte)

I.M. Sauer, N. Obermayer, D. Kardassis , T. Theruvath and J.C. Gerlach

Annals of the New York Academy of Sciences 2001, 944: 308-320 (ISBN: 1-57331-342-4)

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