Purinergic signaling in hepatocellular carcinoma | Non-invasive diagnostics

Dr. rer. nat. Katrin Splith is the lab manager of the Schmelzle lab at the Experimental Surgery. She conducts research to evaluate the clinical relevance of cellular and non-cellular immune responses in ACLF. She has been studying mechanisms of liver regeneration, focusing on the possible role of stem cells, cfDNA and microparticles. In addition, she conducts research on the importance of purinergic signaling in liver regeneration and hepatocellular carcinoma.

Dr. Splith studied chemistry at the University of Leipzig. In 2011, she completed her doctorate with the topic "Delivery of Bioactive Organometallic Compounds by an Antimicrobial Peptide-Derived Carrier" at the Institute of Biochemistry in Leipzig. After a short Postdoctoral stay at the Institute of Biochemistry in Cologne, she became laboratory manager in Prof. Dr. Schmelzle's research group at the Translational Centre for Regenerative Medicine (TRM), University of Leipzig in 2012. She rejoint Prof. Dr. Schmelzle's research group in 2016 at the Charité - Universitätsmedizin Berlin.