2019
Macrosteatosis is a huge problem in liver transplantation – however, not the only one we face
S. Moosburner, I.M. Sauer, J.M.G.V, Gassner, C. Schleicher, D. Bösebeck, A. Rahmel, J. Pratschke, N. Raschzok
2019
Macrosteatosis is a huge problem in liver transplantation – however, not the only one we face
S. Moosburner, I.M. Sauer, J.M.G.V, Gassner, C. Schleicher, D. Bösebeck, A. Rahmel, J. Pratschke, N. Raschzok
Operieren im digitalen Raum – Mixed Reality in der Chirurgie [Operating within the digital space – mixed reality in surgery]
I.M. Sauer, M. Queisner, M. Pogorzhelskiy, J. Pratschke
Diagnostic Biomarkers to Diagnose Acute Allograft Rejection After Liver Transplantation: Systematic Review and Meta-Analysis of Diagnostic Accuracy Studies
F. Krenzien, E. Keshi, K. Splith, S. Griesel, K. Kamali, I.M. Sauer, L. Feldbrügge, J. Pratschke, A. Leder, M. Schmelzle
Impact of Percoll purification on isolation of primary human hepatocytes
R. Horner, J.G.M.V. Gassner, M. Kluge, P. Tang, S. Lippert, K.H. Hillebrandt, S. Moosburner, A. Reutzel-Selke, J. Pratschke, I.M. Sauer, N. Raschzok
First Healthy Baby After Deceased Donor Uterus Transplantation: Birth to a New Era?
M.M. Maurer, I.M. Sauer, J. Pratschke, S.G. Tullius
Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice
S. Wabitsch, C. Benzing, F. Krenzien, K. Splith, P.K. Haber, A. Arnold, M. Nösser, C. Kamali, F. Hermann, C. Günther, D. Hirsch, I.M. Sauer, J. Pratschke, M. Schmelzle
Mixed and Augmented Reality – Why Surgeons Should Care
M. Queisner, J. Pratschke, I.M. Sauer
Composite tissue allotransplantation: opportunities and challenges
J. Iske, Y. Nian, R. Maenosono, M. Maurer, I.M. Sauer, S.G. Tullius
High donor age for liver transplantation : Tackling organ scarcity in Germany
S. Moosburner, P.V. Ritschl, L. Wiering, J.M.G.V. Gassner, R. Öllinger , J. Pratschke, i.M. Sauer, N. Raschzok
Liver Assist Systems for Bridging to Transplantation: Devices and Concepts
N. Raschzok, K.H. Hillebrandt, I.M. Sauer
Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats
J. Albrecht, D. Polenz, A.A. Kühl, J.M.M. Rogasch, A. Leder, I.M. Sauer, M. Babos, G. Mócsai, N. Beindorff, I.G. Steffen, W. Brenner, E.J. Koziolek
2018
Real world usability analysis of two augmented reality headsets in visceral surgery.
S. Moosburner, C. Remde, P. Tang, M. Queisner, N. Haep, J. Pratschke, I.M. Sauer
Prevalence of Steatosis Hepatis in the Eurotransplant Region: Impact on Graft Acceptance Rates
S. Moosburner, J.M.G.V. Gassner, M. Nösser, J. Pohl, D. Wyrwal, F. Claussen, P.V. Ritschl, D. Dragun, J. Pratschke, I.M. Sauer, N. Raschzok
Improvement of normothermic ex vivo machine perfusion of rat liver grafts by dialysis and Kupffer Cell inhibition with glycine
J.M.G.V. Gassner, M. Nösser, S. Moosburner, R. Horner, P. Tang, L. Wegener, D. Wyrwal, F. Claussen, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
The nanomolar sensing of nicotinamide adenine dinucleotide in human plasma using a cycling assay in albumin modified simulated body fluids
P. Brunnbauer, A. Leder, C. Kamali, K. Kamali, E. Keshi, K. Splith, S. Wabitsch, P. Haber, G. Atanasov, L. Feldbrügge, I.M. Sauer, J. Pratschke, M. Schmelzle, F. Krenzien
Tumor-stromal cross-talk modulating the therapeutic response in pancreatic cancer
C.C.M. Neumann, E. von Hörschelmann, A. Reutzel-Selke, E. Seidel, I.M. Sauer, J. Pratschke, M. Bahra, R.B. Schmuck
The predictive value of the LiMax-test for the isolation of primary human hepatocytes
R.D. Major, M. Kluge, M. Jara, M. Nösser, R. Horner, J. Gassner, B. Struecker, P. Tang, S. Lippert, A. Reutzel-Selke, D. Geisel, T. Denecke, M. Stockmann, J. Pratschke, I.M. Sauer, N. Raschzok
Liver Transplantation and Liver Resection for Cirrhotic Patients with Hepatocellular Carcinoma: Comparison of Long-Term Survivals
F. Krenzien, M. Schmelzle, B. Struecker, N. Raschzok, C. Benzing, M. Jara, M. Bahra, R. Öllinger, I.M. Sauer, A. Pascher, J. Pratschke, A. Andreou
Living-Donor Liver Transplant: An Analysis of Postoperative Outcome and Health-Related Quality of Life in Liver Donors
C. Benzing, M. Schmelzle, R. Oellinger, K. Gruettner, A.K. Muehlisch, N. Raschzok, I.M. Sauer, M. Bahra, J. Pratschke, S. Guel-Klein
2017
Incidence and Risk Factors of Symptomatic Hiatal Hernia Following Resection for Gastric and Esophageal Cancer
A. Andreou, S. Pesthy, B. Struecker, M. Dadras, J. Raakow, S. Knitter, G. Duwe, I.M. Sauer, A.S. Beierle, C. Denecke, S. Chopra, J. Pratschke, M. Biebl
Plasma expansion is key for sustained liver function and viability during normothermic and subnormothermic ex vivo machine perfusion in a rat model
J.M.G.V. Gassner, M. Nösser, R. Horner, K.H. Hillebrandt, S. Moosburner, L. Wegener, P. Demko, R. Arsenic, B. Struecker, J. Pratschke, I.M. Sauer, N. Raschzok
Evaluation of Anastomotic Leak after Esophagectomy for Esophageal Cancer:
Typical Time Point of Occurrence, Mode of Diagnosis, Value of Routine Radiocontrast Agent Studies and Therapeutic Options
B. Struecker, A. Andreou, S. Chopra, A.C. Heilmann, J. Spenke, C. Denecke, I.M. Sauer, M. Bahra, J. Pratschke, M. Biebl
Mixed Reality in visceral surgery – development of a suitable workflow and evaluation of intraoperative use-cases
I.M. Sauer, M. Queisner, P. Tang, S. Moosburner, O. Hoepfner, R. Horner, R. Lohmann, J. Pratschke
The magnetic field of magnetic resonance imaging systems does not affect cells labeled with micrometer-sized iron oxide particles
M. Kluge, A. Leder, K.H. Hillebrandt, B. Struecker, D. Geisel, T. Denecke, R.D. Major, A. Reutzel-Selke, P. Tang, S. Lippert, Ch. Schmidt, J. Pratschke, I.M. Sauer, N. Raschzok
Computed tomography-based survey of the vascular anatomy of the juvenile Göttingen minipig
J. Siefert, K.H. Hillebrandt, M. Kluge, D. Geisel, P. Podrabsky, T. Denecke, M. Nösser, J. Gassner, A. Reutzel-Selke, B. Strücker, M.H. Morgul, S. Guel-Klein, J.K. Unger, A. Reske, J. Pratschke, I.M. Sauer, N. Raschzok
Isolation, characterization and cold storage of cells isolated from diseased explanted livers
E. Belaschk, S. Rohn, R. Mukiibi, A. Reutzel-Selke, P. Tang, B. Sawitzki, J. Pratschke, I.M. Sauer, M.T. Mogl
Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans
H. Napierala, K. Hillebrandt, N. Haep, P. Tang, M. Tintemann, J. Gassner, M. Noesser, H. Everwien, N. Seiffert, M. Kluge, E. Teegen, D. Polenz, S. Lippert, D. Geisel, A. Reutzel-Selke, N. Raschzok, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker
The value of microparticles in detecting acute rejection episodes after liver transplantation
M.H. Morgul, K. Splith, C. Leonhardt, N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, A. Andreou, C. Atanasov, C. Benzing, F. Krenzien, H.M. Hau, P. Felgendreff, S. Klunk, J. Pratschke, I.M. Sauer, M. Schmelzle
Bovine serum albumine-glutaraldehyde sealed fish-mouth closure of the pancreatic remnant during distal pancreatectomy
F. Klein, I.M. Sauer, J. Pratschke, M. Bahra
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism
C. von Loeffelholz, S. Lieske, F. Neuschäfer-Rube, D.M. Willmes, N. Raschzok , I.M. Sauer, J. König, M. Fromm, P. Horn, A. Chatzigeorgiou, A. Pathe-Neuschäfer-Rube, J. Jordan, A.F. Pfeiffer, C. Mingrone, S.R. Bornstein, P. Stroehle, C. Harms, F.T. Wunderlich, S.L. Helfand , M. Bernier, R. de Cabo, G.I. Shulman, T. Chavakis, G.P. Püschel, A.L. Birkenfeld
Bile: miRNA pattern and protein based biomarkers may predict acute cellular rejection after liver transplantation
R.B. Schmuck, A. Reutzel-Selke, N. Raschzok, M.H. Morgul, B. Struecker, S. Lippert, C. de Carvalho Fischer, M. Schmelzle, S. Boas-Knoop, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer
Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection
G. Duwe, S. Knitter, S. Pesthy, A.S. Beierle, M. Bahra, M. Schmelzle, R.B. Schmuck, P. Lohneis, N. Raschzok, R. Öllinger, M. Sinn, B. Struecker, I.M. Sauer, J. Pratschke, A. Andreou
New technique for obesity surgery: internal gastric plication technique using intragastric single-port (IGS-IGP) in an experimental model
V. Müller, P. Fikatas, S. Gül, M. Noesser, K.T. Fuehrer, I. Sauer, J. Pratschke, R. Zorron
Routine radiologic contrast agent examination after gastrectomy for gastric cancer is not useful
B. Struecker, S. Chopra, A.C. Heilmann, J. Spenke, C. Denecke, I.M. Sauer, M. Bahra, J. Pratschke, A. Andreou, M. Biebl
Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions
B. Struecker, A. Butter, K. Hillebrandt, D. Polenz , A. Reutzel-Selke, P. Tang, S. Lippert, A. Leder, S. Rohn, D. Geisel, T. Denecke, K. Aliyev, K. Jöhrens, N. Raschzok, P. Neuhaus, J. Pratschke, I.M. Sauer
2016
Evolution of graft morphology and function after recellularization of decellularized rat livers
A. Butter, K. Aliyev, K.-H. Hillebrandt, N. Raschzok, M. Kluge, N. Seiffert, P. Tang, H. Napierala, M.I. Ashraf, A. Reutzel-Selke, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker
The impact of tumor cell proliferation on occult micrometastases, tumor recurrence and patient outcome following resection for liver malignancies
A. Andreou, M. Schmelzle, I.M. Sauer, M. Bahra, J. Pratschke
Hepatocyte isolation after laparoscopic liver resection
R. Horner*, M. Kluge*, R.M. Major, A. Reutzel-Selke, J. Gassner, M. Nösser, B. Strücker, M.H. Morgül, J. Pratschke, I.M. Sauer, N. Raschzok
Allogeneic liver transplantation and subsequent syngeneic hepatocyte transplantation in a rat model – proof of concept for in vivo tissue engineering
S. Rohn, J. Schroeder, H. Riedel, D. Polenz, K. Stanko, A. Reutzel-Selke, P. Tang, L. Brusendorf, N. Raschzok, P. Neuhaus, J. Pratschke, B. Sawitzki, I.M. Sauer, M.T. Mogl
microRNA signatures in peripheral blood fail to detect acute cellular rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R. Schmuck, L. Tannus, M. Morgul, C. Dietel, A. Leder, B. Struecker, S. Lippert, H. Sallmon, M. Schmelzle, M. Bartels, S. Jonas, J. Pratschke, I.M. Sauer
Single Pass Albumin Dialysis (SPAD) – A dose finding study to define optimal albumin concentration and dialysate flow
R.B. Schmuck, G.-H. Nawrot, P. Fikatas, A. Reutzel-Selke, J. Pratschke, I.M. Sauer
Human hepatocyte isolation: Does portal vein embolization affect the outcome?
M. Kluge, A. Reutzel-Selke, H. Napierala, K.H. Hillebrandt, R.D. Major, B. Struecker, A. Leder, J. Siefert, P. Tang, S. Lippert, D. Seehofer, J. Pratschke, I.M. Sauer, N. Raschzok
Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver
C. von Loeffelholz, S. Döcke, J.F. Lock, S. Lieske, P. Horn, J. Kriebel, S. Wahl, P. Singmann, T. de Las Heras Gala, H. Grallert, N. Raschzok, I.M. Sauer, R. Heller, G. Jahreis, R.A. Claus, M. Bauer, M. Stockmann, A.L. Birkenfeld, A.F. Pfeiffer
Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue – A statistical model based on stepwise penalized logistic regression
M.H. Morgul, S. Klunk, Z. Anastasiadou, U. Gauger, C. Dietel, A. Reutzel-Selke, P. Felgendref, H.M. Hau, H.M. Tautenhahn, R.B. Schmuck, N. Raschzok, I.M. Sauer, M. Bartels
Predictive factors for extrahepatic recurrence of hepatocellular carcinoma following liver transplantation
A. Andreou, M. Bahra, M. Schmelzle, R. Öllinger, R. Sucher, I.M. Sauer, S. Guel-Klein, B. Struecker, D. Eurich, F. Klein, A. Pascher, J. Pratschke, D. Seehofer
Risk factors for bile leakage after hepatectomy
B. Struecker, A. Andreou, I.M. Sauer, J. Pratschke, D. Seehofer
Implantation of a tissue engineered Neo Bile Duct in domestic pigs
B. Struecker, K. Hillebrandt, N. Raschzok, K. Jöhrens, A. Butter, P. Tang, A. Andreou, H. Napierala, D. Polenz, A. Reutzel-Selke, T. Denecke, J. Pratschke, I.M Sauer
The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C
N. Raschzok, E. Schott, A. Reutzel-Selke, I. Damrah, S. Gül-Klein, B. Strücker, I.M. Sauer, J. Pratschke, D. Eurich, M. Stockmann
The Impact of Obesity on Outcomes Following Resection for Gastric Cancer
B. Struecker, M. Biebl, M. Dadras, S. Chopra, C. Denecke, J. Spenke, A.C. Heilmann, M. Bahra, I.M. Sauer, J. Pratschke, A. Andreou
Acute graft dysfunction 17 years after liver transplant: A challenging clinical and histologic manifestation of hepatitis E
K.H. Hillebrandt, R. Arsenic, J. Hofmann, D. Eurich, S. Gül, B. Strücker, I.M. Sauer, J. Pratschke, M. Stockmann, N. Raschzok
2015
microRNAs in liver tissue engineering – new promises for failing organs
N. Raschzok, H. Sallmon, J. Pratschke, I.M. Sauer
Tumor DNA-index and α-fetoprotein level define outcome following liver transplantation for advanced hepatocellular carcinoma.
Andreou A, Bahra M, Guel S, Struecker B, Sauer IM, Klein F, Pascher A, Pratschke J, Seehofer D.
Procedure for Decellularization of Rat Livers in an Oscillating-pressure Perfusion Device
K. Hillebrandt, D. Polenz, A. Butter, P. Tang, A. Reutzel-Selke, A. Andreou, H. Napierala, N. Raschzok, J. Pratschke, I.M. Sauer, B. Struecker
CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, M.H. Morgul, U. Gauger,K.A. Prabowo, L.-M. Tannus, A. Leder, B. Struecker, S. Boas-Knoop, M. Bartels, S. Jonas, Ch. Lojewski, G. Puhl, D. Seehofer, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer
Tissue Engineered Grafts – 160 Years After R. Virchow's Omnis Cellula e Cellula
I.M. Sauer
Micron-sized iron oxide-containing particles for microRNA-targeted manipulation and MRI-based tracking of transplanted cells
A. Leder*, N. Raschzok*, C. Schmidt, D. Arabacioglu, A. Butter, S. Kolano, L.S. de Sousa Lisboa, W. Werner, D. Polenz, A. Reutzel-Selke, J. Pratschke, I.M. Sauer
2014
Liver support strategies: cutting-edge technologies
B. Struecker, N. Raschzok, I.M. Sauer
Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process
B. Struecker, K. Hillebrandt, R. Voitl, A. Butter, R.B. Schmuck, A. Reutzel-Selke, D. Geisel, K. Joehrens, P.A. Pickerodt, N. Raschzok, G. Puhl, P. Neuhaus, J. Pratschke, I.M. Sauer
Independent Effects of Sham Laparotomy and Anesthesia on Hepatic microRNA Expression in Rats
W. Werner, H. Sallmon, A. Leder, S. Lippert, A. Reutzel-Selke, M.H. Morgül, S. Jonas, S. Dame, P. Neuhaus, J. Iacomini, S.G. Tullius, I.M. Sauer, N. Raschzok
2013
Functionalizable silica-based micron-sized iron oxide particles for cellular Magnetic Resonance Imaging
N. Raschzok, C.M. Langer, Ch. Schmidt, K.H. Lerche, N. Billecke, K. Nehls, N.B. Schlüter, A. Leder, S. Rohn, M.T. Mogl, L. Lüdemann, L. Stelter, U.K. Teichgräber, P. Neuhaus, I.M. Sauer
Identification of a novel human polyomavirus in organs of the gastrointestinal tract
Korup S, Rietscher J, Calvignac-Spencer S, Trusch F, Hofmann J, Moens U, Sauer I, Voigt S, Schmuck R, Ehlers B.
Elevated hepatic chemerin gene expression in progressed human non-alcoholic fatty liver disease
S. Döcke, J.F. Lock, A.L. Birkenfeld, S. Hoppe, S. Lieske, A. Rieger, N. Raschzok, I.M. Sauer, S. Florian, M.A. Osterhoff, R. Heller, K. Herrmann, S. Lindenmüller, P. Horn, M. Bauer, M.O. Weickert, P. Neuhaus, M. Stockmann, M. Möhlig, A.Fh. Pfeiffer C. von Loeffelholz
Evaluation of Arginine deiminase treatment in melanoma xenografts using 18F-FLT PET
S. Döcke, J.F. Lock, A.L. Birkenfeld, S. Hoppe, S. Lieske, A. Rieger, N. Raschzok, I.M. Sauer, S. Florian, M.A. Osterhoff, R. Heller, K. Herrmann, S. Lindenmüller, P. Horn, M. Bauer, M.O. Weickert, P. Neuhaus, M. Stockmann, M. Möhlig, A.Fh. Pfeiffer C. von Loeffelholz
Noninvasive monitoring of liver cell transplantation
N. Raschzok, H.M. Morgül, L. Stelter, I.M. Sauer
Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices
G. Tong, S. Endersfelder, L.M. Rosenthal, S. Wollersheim, I.M. Sauer, C. Bührer, F. Berger, K.R. Schmitt
Identification of a novel human polyomavirus in organs of the gastrointestinal tract
S. Korup, J. Rietscher, S. Calvignac-Spencer, F. Trusch, J. Hofmann, U. Moens, I. Sauer, S. Voigt, R. Schmuck, B. Ehlers
2012
Feasibility of fast dynamic MRI for non-invasive monitoring during ectopic liver cell transplantation to the spleen in a porcine model
N. Raschzok, J. Pinkernelle, N. Billecke, K. Nehls, M. Powerski, I.M. Sauer, U. Teichgraber
A novel cannulation technique for isolation of human hepatocytes from explanted, diseased whole livers
D.C. Kehr, N. Raschzok, I.M. Sauer
Liver regeneration after partial hepatectomy: inconsistent results of expression screenings for human, mouse, and rat miRNAs
N. Raschzok, H. Sallmon, C. Dame, I.M. Sauer
An operational concept for long-term cinemicrography of cells in mono- and co-culture under highly controlled conditions - the SlideObserver
N. Billecke, N. Raschzok, S. Rohn, M.H. Morgul, R. Schwartlander, M. Mogl, S. Wollersheim, K.R. Schmitt*, I.M. Sauer*
Improvement of the cold storage of isolated human hepatocytes
G. Pless, I.M. Sauer, U. Rauen
2011
Temporal expression profiles indicate a primary function for microRNA during the peak of DNA replication after rat partial hepatectomy
N. Raschzok, W. Werner, H. Sallmon, N. Billecke, C. Dame, P. Neuhaus, I.M. Sauer
Labelling of primary human hepatocytes with micron-sized iron oxide particles in suspension culture suitable for large-scale preparation
N.N. Kammer, N. Billecke, M.H. Morgul, M.K. Adonopoulou, M. Mogl, M.D. Huang, S. Florek, K.R.L. Schmitt, N. Raschzok, I.M. Sauer
CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells
G. Rago, C.M. Langer, C. Brackman, J.P. Day, K.F. Domke, N. Raschzok, C. Schmidt, I.M. Sauer, A. Enejder, M.T. Mogl, M. Bonn
The APACHE III score as preoperative indicator of patient outcome in liver transplantation after fulminant hepatic failure
P. Fikatas, F. Ulrich, J.E. Lee, I.M. Sauer, S. Chopra, S.C. Schmidt, A. Pascher, J. Pratschke
In vitro evaluation of magnetic resonance imaging contrast agents for labeling human liver cells: implications for clinical translation
N. Raschzok, D.A. Muecke, M.K. Adonopoulou, N. Billecke, W. Werner, N.N. Kammer, A. Zielinski, P.A. Behringer, F. Ringel, M.D. Huang, P. Neuhaus, U. Teichgräber, I.M. Sauer
Continuous veno-venous single-pass albumin hemodiafiltration in children with acute liver failure
H. Ringe, V. Varnholt, M. Zimmering, W. Luck, A. Gratopp, K. König, S. Reich, I.M. Sauer, G. Gaedicke, U. Querfeld
2010
Monitoring of liver cell transplantation in a preclinical swine model using Magnetic Resonance Imaging
N. Raschzok, U. Teichgräber, N. Billecke, A. Zielinski, K. Steinz, N.N. Kammer, M.H. Morgul, S. Schmeisser, M.K. Adonopoulou, L. Morawietz, B. Hiebl, R. Schwartlander, W. Rüdinger, B. Hamm, P. Neuhaus, I.M. Sauer
Modification of aminosilanized superparamagnetic nanoparticles: feasibility of multimodal detection using 3T MRI, small animal PET, and fluorescence imaging
L. Stelter, J. Pinkernelle, R. Michel, R. Schwartlander, N. Raschzok, M.H. Morgul, M. Koch, T. Denecke, H. Amthauer, J. Ruf, A. Jordan, B. Hamm, I.M. Sauer, U. Teichgraber
Aging of the liver graft and functional quality in the absence of recurrent disease: a 10 year histological follow-up
M. Schmeding, I.M. Sauer, K. Hartwig, T. Theruvath, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann
Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro
A. Diestel, S. Troeller, N. Billecke, I.M. Sauer, F. Berger, K.R.L. Schmitt
European Journal of Neuroscience, 2010; 31: 779-787
2009
Quantification of Cell Labelling with Micron-Sized Iron Oxide Particles Using Continuum Source Atomic Absorption Spectrometry
N. Raschzok, N. Billecke, N.N. Kammer, M.H. Morgul, M.K. Adonopoulou, I.M. Sauer, S. Florek, H. Becker-Ross, M.-D. Huang
Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes
T. Deurholt, N.P. van Til, A.A. Chhatta, L. ten Bloemendaal, R. Schwartlander, C. Payne, J.N. Plevris, I.M. Sauer, R.A. Chamuleau, R.P. Elferink, J. Seppen, R. Hoekstra
Aspergillus spondylodiscitis after multivisceral transplantation
U.A. Gerlach, S. Kohler, I.M. Sauer, D. Joerres, F. Kandziora, P. Neuhaus, J. Pratschke, A. Pascher
Tacrolimus and methylprednisolone prevent hypothermia induced endothelial dysfunction
A. Diestel, N. Billecke, J. Roessler, B. Schmitt, S. Troeller, R. Schwartlander, F. Berger, I.M. Sauer*, K.R.L. Schmitt*
Journal of Heart and Lung Transplantation, 2009, 28: 718-724 (IF: 3.514)
Successful treatment of invasive sphenoidal, pulmonary and intracerebral aspergillosis after multivisceral transplantation
S. Kohler, U. Gerlach, O. Guckelberger, I.M. Sauer, D. Jörres, P. Neuhaus, J. Pratschke, A. Pascher
2008
Imaging of Primary Human Hepatocytes Using Micron-Sized Iron Oxide Particles and Clinical Magnetic Resonance Tomography
N. Raschzok*, M.H. Morgul*, J. Pinkernelle, F.W.R. Vondran, N. Billecke, N.N. Kammer, G. Pless, M.K. Adonopoulou, C. Leist, L. Stelter, U. Teichgraber, R. Schwartlander, I.M. Sauer
Tracking of primary human hepatocytes with clinical MRI – initial results with Tat-peptide modified superparamagnetic iron oxide particles
M.H. Morgul*, N.Raschzok*, R. Schwartlander, F.W.R. Vondran, R. Michel, L. Stelter, J. Pinkernelle, A. Jordan, U. Teichgraber, I.M. Sauer
Isolation of primary human hepatocytes after partial hepatectomy – Criteria for identification of the most promising liver specimen
F.W.R.Vondran, E. Katenz, R. Schwartlander, M.H. Morgul, N. Raschzok, X.B.Gong, X.D. Cheng, D. Kehr, I.M. Sauer
Graft versus host disease after liver transplantation - a single center experience and review of literature
S. Kohler, A. Pascher, G. Junge, I.M. Sauer, M. Nagy, C. Schönemann, M. Koch, U. Neumann, J. Pratschke, P. Neuhaus
Heterotopic ileal pancreas with lipoma and coexisting fibromatosis associated with a rare case of gastrointestinal bleeding. A case report and review of the literature.
P. Fikatas, I.M. Sauer, M. Mogl, C. Menenakos, A. Luegering, G. Schumacher, J. Langrehr, P. Neuhaus
Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: Technical aspects
A. Spinelli, G. Schumacher, C. Benckert, I.M. Sauer, M. Schmeding, M. Glanemann, U.P. Neumann, S. Jonas, P. Neuhaus
2007
Continuously microscopically observed and process controlled cell culture within the SlideReactor – proof of a new concept for cell characterization
R. Schwartlander, J. Schmid, B. Brandenburg, E. Katenz, F.W.R. Vondran, G. Pless, X. Cheng, A. Pascher, P. Neuhaus, I.M. Sauer
Somatostatin receptor subtype-2-deficient mice with diet-induced obestiy have hyperglycemia, non-fasting hyperglucagonemia and decreased hepatic glycogen deposition
V. Singh, C. Grotzinger, K.W. Nowak, S. Zacharias, E. Goncz, G. Pless, I.M. Sauer, I. Eichhorn, B. Pfeiffer-Guglielmi, B. Hamprecht, B. Wiedenmann, U. Plockinger, M.Z. Strowski
Cryopreservation of primary human hepatocytes – the benefit of trehalose as an additional cryoprotective agent
E. Katenz, F.W.R. Vondran, R. Schwartlander, G. Pless, X. Gong, X. Cheng, P. Neuhaus, I. M. Sauer
Influence of basiliximab induction therapy on long term outcome after liver transplantation, a prospectively randomised trial
M. Schmeding, I.M. Sauer, A. Kiessling, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann
First in vitro comparison of two bioartificial liver support systems: MELS CellModule and AMC-BAL
P.P.C. Poyck, G. Pless, R. Hoekstra, S. Roth, A.C.W.A. van Wijk, R. Schwartlander, T.M. van Gulik, I.M. Sauer, R.A.F.M. Chamuleau
2006
Evaluation of primary human liver cells in bioreactor cultures for extracorporeal liver support on the basis of urea production
G. Pless, I. Steffen, K. Zeilinger, I.M. Sauer, E. Katenz, D.C. Kehr, S. Roth, T. Mieder, R. Schwartlander, Ch. Müller, B. Wegner, M. S. Hout, P. Neuhaus, J.C. Gerlach
Cell-free artificial liver support
I.M. Sauer, U. Baurmeister
Therapeutic Apheresis and Dialysis 2006, 10: 105-107 (IF: 1.177)
Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature
A. Spinelli, G. Schumacher, A. Pascher, E. Lopez-Hanninen, H. Al-Abadi, C. Benckert, I.M. Sauer, J. Pratschke, U.P. Neumann, S. Jonas, J.M. Langrehr, P. Neuhaus
2005
Novel system for efficient gene transfer into primary human hepatocytes via cell permeable HBV virus-like particle
B. Brandenburg, L. Stockl, C. Gutzeit, M. Roos, J. Lupberger, R. Schwartlander, H. Gelderblom, I.M. Sauer, P.H. Hofschneider, E. Hildt
The SlideReactor - a simple hollow fiber based bioreactor suitable for light microscopy
I.M. Sauer, R. Schwartlander, J. Schmid, E. Efimova, F.W.R. Vondran, D. Kehr, G. Pless, A. Spinelli, B. Brandenburg, E. Hildt, and P. Neuhaus
Clinical results of intestinal and multivisceral transplantation at the Charité, Berlin
A. Pascher, J. Klupp, R.J. Schulz, S. Kohler, G. Junge, I.M. Sauer, W. Veltzke-Schlieker, A. Adler, O. Guckelberger, N.C. Nussler, A. Dignass, J.M. Langrehr, P. Neuhaus
In vitro evaluation of the transportability of viable primary human liver cells originating from discarded donor organs in bioreactors
I.M. Sauer, R. Schwartlander, O. van der Jagt, I. Steffen, E. Efimova, G. Pless, D.C. Kehr, D. Kardassis, J.H. Fruhauf, J.C. Gerlach, P. Neuhaus
Artificial Organs 2005, 29: 141-151 (IF: 1.946)
“Blogs” and “Wikis” are valuable software tools for communication within research groups
I.M. Sauer, D. Bialek, E. Efimova, R. Schwartlander, G. Pless, P. Neuhaus
The European artificial organ scene: present status
R. Vanholder, J. de Cañizo, I.M. Sauer, B Stegmayr
Bioartificial liver: current status
G. Pless, I.M. Sauer
2004
In vitro comparison of the Molecular Adsorbent Recirculation System (MARS) and Single Pass Albumin Dialysis (SPAD)
I.M. Sauer, M. Goetz, I. Steffen, G. Walter, D.C. Kehr, R. Schwartlander, Y.J. Hwang, A. Pascher, J.C. Gerlach, P. Neuhaus
Bilirubin-adsorption in 23 critically ill patients with liver failure
R. Senf, R. Klingel, S. Kurz, S. Tullius, I.M. Sauer, U. Frei, R. Schindler
2003
The use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors – a morphological study
J.C. Gerlach, K. Mutig, I.M. Sauer, P. Schrade, E. Efimova, T. Mieder, G. Nauman, A. Grünwald, G. Pleß, A. Mas, S. Bachmann, P. Neuhaus, K. Zeilinger
Extracorporeal Liver Support based on Primary Human Liver Cells and Albumin Dialysis – Treatment of a Patient with Primary Graft Non-Function
I.M. Sauer, K. Zeilinger, G. Pless, D. Kardassis, T. Theruvath, A. Pascher, M. Goetz, P. Neuhaus, J. C. Gerlach
Porcine endogenous retroviruses (PERVs): No infection in patients treated with a bioreactor based on porcine liver cells
M. Irgang, I.M. Sauer, A. Karlas, K. Zeilinger, J.C. Gerlach, R. Kurth, P. Neuhaus, J. Denner
Clinical extracorporeal hybrid liver support – phase I study with primary porcine liver cells
I.M. Sauer, D. Kardassis, K. Zeillinger, A. Pascher, A. Gruenwald, G. Pless, M. Irgang, M. Kraemer, G. Puhl, J. Frank, A.R. Müller, Th. Steinmüller, J. Denner, P. Neuhaus, J. C. Gerlach
Late Graft Loss After Intestinal Transplantation in an Adult Patient as a Result of Necrotizing Enterocolitis
A. Pascher, C. Radke, A. Dignass, R. Schulz, I.M. Sauer, K. Platz, J. Klupp, P. Neuhaus, A. Mueller
Recovery of Preservation Injured Primary Human Hepatocytes and Nonparenchymal Cells to Tissue-Like Structures in Large-Scale Bioreactors for Liver Support: An Initial Transmission Electron Microscopy Study
J.C. Gerlach, K. Zeilinger, A. Grebe, G. Puhl, G. Pless, I.M. Sauer, A. Grunwald, N. Schnoy, C. Muller, P. Neuhaus
Einsatz biologischer Leberunterstützungssysteme bei der Therapie des Leberversagens – Modular Extracorporeal Liver Support (MELS)
T.P. Theruvath, I.M. Sauer, D. Kardassis, N. Obermayer, A. Pascher, M. Goetz, A.R. Mueller, Th. Steinmueller, P. Neuhaus, J.C. Gerlach
Verdauungskrankheiten 2003, 21: 32-40
2002
Concept for modular extracorporeal liver support for the treatment of acute hepatic failure
I.M. Sauer, P. Neuhaus, J.C. Gerlach
Extracorporeal liver support: Porcine or human cell based systems?
J.C. Gerlach, K. Zeilinger, I.M. Sauer, T. Mieder, G. Naumann, A. Grünwald, G. Pless, G. Holland, A. Mas, J. Vienken, P. Neuhaus
Primary human liver cells as source for modular extracorporeal liver support – a preliminary report
I.M. Sauer, K. Zeilinger, N. Obermayer, G. Pless, A. Pascher, T. Mieder, S. Roth, M. Goetz, D. Kardassis, A. Mas, P. Neuhaus, J.C. Gerlach
International Journal of Artificial Organs 2002, 25: 1001-1005 (IF: 1.192)
Analysis of allogeneic versus xenogeneic auxiliary organ perfusion in liver failure reveals superior efficacy of human livers
A. Pascher, I.M. Sauer, P. Neuhaus
International Journal of Artificial Organs 2002, 25: 1006-1012 (IF: 1.192)
Three-dimensional Co-culture of Primary Human Liver Cells in Bioreactors for In Vitro Drug Studies: Effects of the Initial Cell Quality on the Long-term Maintenance of Hepatocyte-specific Functions.
K. Zeilinger K, I.M. Sauer, G. Pless, C. Strobel, J. Rudzitis, A. Wang, A.K. Nussler, A. Grebe, L. Mao, S.H. Auth, J. Unger, P. Neuhaus, J.C. Gerlach
Modified surgical technique in clinical small bowel transplantation: donor and recipient management.
A. Mueller, A. Pascher, K. Platz, N. Nussler, R. Schulz,D. Horch,T. Melitz,I. M. Sauer, R. Eisele,U. Settmacher,A. Dignass,E. Lopez-Henninen,H. Weidemann,P. Neuhaus
Transplantation Proceedings 2002; 34: 2265 (IF: 0.478)
Living-Donation Liver Transplantation for Hepatocellular Carcinoma: Time to Drop the Limitations?
Th. Steinmüller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Müller, U.Settmacher, P. Neuhaus
Transplantation Proceedings 2002; 34: 2263-2264 (IF: 0.478)
A method to assess biochemical activity of liver cells during clinical application of extracorporeal liver support
A. Mundt, G. Puhl, A. Müller, I. Sauer, C. Müller, R. Richard, C. Fotopoulou, R. Doll, G. Gäblein, W. Höhn, R. Hofbauer, P. Neuhaus, J. Gerlach
Modular Extracorporeal Liver Support (MELS)
I.M. Sauer, J.C. Gerlach
Extracorporeal Liver Perfusion as Hepatic Assist in Acute Liver Failure - A Review of World Experience
A. Pascher, I.M. Sauer, C. Hammer, J.C. Gerlach, P. Neuhaus
[Right lobe living donor liver transplantation between adults]
T. Steinmuller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Muller, U. Settmacher , P. Neuhaus
Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.
K.P. Platz, A. Pascher, R.J. Schulz, N.C. Nussler, I.M. Sauer, U. Settmacher, R. Eisele, A. Dignass, E. Lopez-Henninen, P. Neuhaus, A.R. Mueller
Transplantation Proceedings 2002, 34: 906-907 (IF: 0.478)
Monitoring of immunosuppression after clinical small bowel transplantation.
A. Pascher, I.M. Sauer, R.J. Schulz, K. Platz, T. Theruvath, A. Dignass, C. Radke, P. Neuhaus, A.R. Mueller
Transplantation Proceedings 2002, 34: 931-933 (IF: 0.478)
2001
Experimental evaluation of a cell module for hybrid liver support
J.C. Gerlach, M. Botsch, D. Kardassis, P. Lemmens, M. Schoen, J. Janke, G. Puhl, J. Unger, M. Kraemer, B. Busse, B. Boehmer, R. Belal, M. Ingenlath, M. Kosan, B. Kosan, J. Sueltmann, A. Patzold, S. Tietze, R. Roissant, C. Mueller, E. Moench, I.M. Sauer, P. Neuhaus
Development of a hybrid liver support system
I.M. Sauer, N. Obermayer, D. Kardassis, T. Theruvath, J.C. Gerlach
Modular Extracorporeal Liver Support (MELS) bei Leberversagen
D. Kardassis, T.P. Theruvath, I.M. Sauer, J.C. Gerlach, P. Neuhaus
Journal für Anästhesie und Intensivbehandlung 2001, 3: 97-99
Split liver and living donation liver transplantation: the Berlin experience.
I.M. Sauer, A. Pascher, Th. Steinmueller, U. Settmacher, A.R. Müller, W.O. Bechstein, P. Neuhaus
Transplantation Proceedings 2001; 33: 1459-1460 (IF: 0.568)
2000
Multiorgantransplantation
I.M. Sauer, A. Pascher, R. Pfitzmann, A.R. Mueller, P. Neuhaus
Chirurgische Praxis 2000, 57: 411-427
TAH Ovalis - Development and in vitro testing of a new electromechanical energy converter for a total artificial heart
I.M. Sauer, J. Frank, A.Spiegelberg, E.S. Bücherl
1999
An unusual case of early pancreas graft loss.
I.M. Sauer, A. Kahl, A.R. Müller, P. Neuhaus, W.O. Bechstein
Proposal of a new electro-mechanical heart: TAH Serpentina
I.M. Sauer, J. Frank, E.S. Bücherl
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