Dr. Karl Hillebrandt is a junior research group leader at Experimental Surgery, Department of Surgery, Charité - Universitätsmedizin Berlin and fellow at the BIH/Charité Clinician Scientist Program. His research focuses on de- and recellularization of tissues as well as organs. His group is specialized on the in-depth characterization of decellularized tissues. Dr. Hillebrandt and his team have implemented proteomic analysis for the characterization of the matrisome of decellularized tissue as well as magnetic resonance elastography for the biomechanical analysis of these tissues. The investigation of these parameters is essential to gain a better understanding of the processes of de- and recellularization. Furthermore, the development of new in vitro matrix-based tumor models for personalized oncological research is another pillar of his research efforts.
Another important research area is the generation of a de-and recellularized ‘Neo-Pancreas’ as an innovative therapeutic approach for type one diabetes.