Selected Publications
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the
Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.

2024

Cytokine-armed vaccinia virus promotes cytotoxicity towards pancreatic carcinoma cells via activation of human intermediary CD56dimCD16dim natural killer cells
R. Wang, M. Hu, I. Lozzi, C.Z.J. Jin, D. Ma, K. Splith, J. Mengwasser, V. Wolf, L. Feldbrügge, P. Tang, L. Timmermann, K.H. Hillebrandt, M. Kirchner, Ph. Mertins, G. Hilfenhaus, Ch. Neumann, Th. Kammertoens, J. Pratschke, T. Malinka, I. Sauer, E. Nössner, Z. Guo, M. Felsenstein

International Journal of Cancer; 2024 – in press

Back

Viscoelastic properties of colorectal liver metastases reflect the tumour cell viability
L.-M. Skrip, S. Moosburner, P. Tang, J. Guo, S. Görner, H. Tzschätzsch, C. Hosse, U. Fehrenbach, A. Arnold, D. Modest, F. Krenzien, W. Schöning, Th. Malinka, J. Pratschke, B. Papke, J.A. Käs, I. Sack, I.M. Sauer, K.H. Hillebrandt

Journal of Translational Medicine; 2024 – in press

Back

Extracellular NAD+ Response to Post-Hepatectomy Liver Failure: Bridging Preclinical and Clinical Findings
C. Kamali, P. Brunnbauer, K. Kamali, Al-H. Saqr, A. Arnold, G. Harman Kamali, J. Babigian, E. Keshi, R. Mohr, M. Felsenstein, S. Moosburner, K. Hillebrandt, J. Bartels, I. Sauer, F. Tacke, M. Schmelzle, J. Pratschke, F. Krenzien

Communications Biology; 2024 – in press

Back

Induced pluripotent stem cell (iPSC) line (EXSURGi001-A) from a patient homozygous for the p.Ala165Thr mutation in the MTARC1 gene
P. Tang, E. Keshi, S. Wilken, L. Wutsdorff, J. Mougnekabol, J. Pratschke, I.M. Sauer N. Haep

Back

Distinctive protein expression in elderly livers in a Sprague-Dawley rat model of normothermic ex vivo liver machine perfusion
M. Zimmer, K.H. Hillebrandt, N.M. Roschke, S. Lippert, O. Klein, G. Nebrich, J.M.G.V. Gassner, F. Strobl, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner

Back

Multinational Analysis of Marginal Liver Grafts Based on the Eurotransplant Extended Donor Criteria
S. Moosburner, M.S. Patel, B.K. Wang, J. Prasadh, R. Öllinger, G. Lurje, I.M. Sauer, P.A. Vagefi, J. Pratschke, N. Raschzok

Annals of Surgery, 2024 – in press

Back

On the relationship between viscoelasticity and water diffusion in soft biological tissues
J. Braun, J. Bernarding, J. Snellings, T. Meyer, P.A. Dantas de Moraes, Y. Safraou, R.G. Wells, J. Guo, H. Tzschätzsch, A. Zappe, K. Pagel, I.M. Sauer, K.H. Hillebrandt, I. Sack

Back

Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization
A. Almalla, L. Elomaa, N. Fribiczer, T. Landes, P. Tang, Z. Mahfouz, B. Koksch, K.H. Hillebrandt, I.M. Sauer, D. Heinemann, S. Seiffert, M. Weinhart

Back

Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
M.I. Ashraf, J. Mengwasser, A. Reutzel-Selke, D. Polenz, K. Führer, S. Lippert, P. Tang, E. Michaelis, R. Catar, J. Pratschke, Ch. Witzel, I.M. Sauer, S.G. Tullius, B. Kern

Back

Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome
N.N. Roschke, K.H. Hillebrandt, D. Polenz, O. Klein, J.M.G.V. Gassner, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner.

Back

Proteomic analysis of decellularized mice liver and kidney extracellular matrices
A.M. Diedrich, A. Daneshgar, P. Tang, O. Klein, A. Mohr, O.A. Onwuegbuchulam, S. von Rueden, K. Menck, A. Bleckmann, M.A. Juratli, F. Becker, I.M. Sauer, K.H. Hillebrandt, A. Pascher, B. Struecker

Back

miRNA as potential biomarkers after liver transplantation: A systematic review
P.F. Koch, K. Ludwig, F. Krenzien, K.H. Hillebrandt, W. Schöning, J. Pratschke, N. Raschzok, I.M. Sauer, S. Moosburner

Back

Improved outcomes after hypothermic oxygenated machine perfusion in liver transplantation-Long-term follow-up of a multicenter randomized controlled trial.
Z. Czigany, D. Uluk, S. Pavicevic, I. Lurje, J. Froněk, Th. Keller, P. Strnad, D. Jiang, T. Gevers, D. Koliogiannis, M. Guba, R.H. Tolba, F.A. Meister, U.P. Neumann, M. Kocik, M. Kysela, I.M. Sauer, N. Raschzok, W. Schöning, I. Popescu, F. Tacke, J. Pratschke, G. Lurje

Back

Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels
A. Almalla, L. Elomaa, L. Bechtella, A. Daneshgar, P. Yavvari, Z. Mahfouz, P. Tang, B. Koksch, I. Sauer, K. Pagel, K.H. Hillebrandt, M. Weinhart

Back

Redefining the Laparoscopic Spatial Sense: AI-based Intra- and Postoperative Measurement from Stereoimages
L. Müller, P. Hemmer, M. Queisner, I. Sauer, S. Allmendinger, J. Jakubik, M. Vössing, N. Kühl

Back

Rise of tissue- and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins  
L. Elomaa, A. Almalla, E. Keshi, K.H. Hillebrandt, I.M. Sauer, M. Weinhart

Back

Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering  
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

Back

Advancing perfusion models: Dual-vessel ex vivo rat liver perfusion based on a clinical setup
F. Strobl, J. Michelotto, V. Muth, S. Moosburner, K. Knaub, M. Zimmer, M. Patel, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner

Back

Body composition is associated with disease aetiology and prognosis in patients undergoing resection of intrahepatic cholangiocarcinoma.
I. Lurje, D. Uluk, S. Pavicevic, M.D. Phan, D. Eurich, U. Fehrenbach, D. Geisel, T.A. Auer, U. Pelzer, D.P. Modest, N. Raschzok, I.M. Sauer, W. Schöning, F. Tacke, J. Pratschke, G. Lurje G

Back

Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok

Back

Bioactive photocrosslinkable resin solely based on refined decellularized small intestine submucosa for vat photopolymerization of in vitro tissue mimics
L. Elomaa, L. Gerbeth, A. Almalla, N. Fribiczer, A. Daneshgar, P. Tang, K. Hillebrandt, S. Seiffert, I.M. Sauer, B. Siegmund, M. Weinhart

Back

Augmenting Image-Guided Procedures through In Situ Visualization of 3D Ultrasound via a Head-Mounted Display
F. von Haxthausen, Ch. Rüger, M.M. Sieren, R. Kloeckner, F. Ernst

Back

Effect of pre-operative chemotherapy on the isolation outcome of primary human hepatocytes
M. Rissel, J. Pohl, S. Moosburner, J. Gaßner, R. Horner, K. Hillebrandt, D. Modest, J. Pratschke, I.M. Sauer, N. Raschzok

Back

2022

Inhibition of Vascular Endothelial Growth Factor Protects against the Development of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Wild-Type but Not in CD39-Null Mice
S. Knitter, G. Duwe, A.S. Beierle, S. Pesthy, P.V. Ritschl, K.H. Hillebrandt, A. Arnold, T. Malinka, D.P. Modest, M. Bahra, J. Pratschke, I.M. Sauer, M. Schmelzle, A. Andreou

Back

Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues
J. Snellings, E. Keshi, P. Tang, A. Daneshgar, E.C. Willma, L. Haderer, O. Klein, F. Krenzien, Th. Malink, P. Asbach, J. Pratschke, I.M. Sauer, J. Braun, I. Sack, K. Hillebrandt

Back

Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N

Back

Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas

Back

VolumetricOR: A new Approach to Simulate Surgical Interventions in Virtual Reality for Training and Education
M. Queisner, M. Pogorzhelskiy, Ch. Remde, J. Pratschke, I.M. Sauer

Back

Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?
M. Felsenstein, F. Lindhammer, M. Feist, K.H. Hillebrandt, L. Timmermann, C. Benzing, B. Globke, D. Zocholl, M. Hu, U. Fehrenbach, B.V. Sinn, U. Pelzer, I.M. Sauer, J. Pratschke, T. Malinka

Back

Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing
J.M. Alves, S. Prado-López, L. Tomás, M. Valecha, N. Estévez-Gómez, P. Alvariño, D. Geisel, D.P. Modest, I.M. Sauer, J. Pratschke, N. Raschzok, C. Sers, S. Mamlouk, D. Posada

Back

Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok

Back

Prognostic and Predictive Molecular Markers in Cholangiocarcinoma
S. Pavicevic, S. Reichelt, D. Uluk, I. Lurje, C. Engelmann, D.P. Modest, U. Pelzer, F. Krenzien, N. Raschzok, C. Benzing, I.M. Sauer, S. Stintzing, F. Tacke, W. Schöning, M. Schmelzle, J. Pratschke, G. Lurje

Back

FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer
N. Raschzok, S. Stintzing, V. Heinemann, G. Rauch, J. Ricke, M. Guckenberger, A. Kurreck, A.H.S. Alig, A. Stahler, L. Bullinger, M. Schmelzle, W. Schöning, G. Lurje, F. Krenzien, O. Haase, B. Rau, B. Gebauer, I.M. Sauer, J. Pratschke, D.P. Modest DP

Back

Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N

Back

[Digital documentation of complications in visceral surgery: possibilities and evaluation of an instrument for quality management]
A. Winter, M.M. Maurer, M. Schmelzle, T. Malinka, M. Biebl, P. Fikatas, D. Kröll, I.M. Sauer, M. Hippler-Benscheidt, J, Pratschke, S. Chopra

Back

Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
E. Keshi, P. Tang, M. Weinhart, H. Everwien, S. Moosburner, N. Seiffert, M. Lommel, U. Kertzscher, B. Globke, A. Reuztel-Selke, B. Strücker, J. Pratschke, I.M. Sauer, N. Haep, K.H. Hillebrandt

Back

Cancer Associated Fibroblasts Derived from Pancreatic Adenocarcinoma and Their Role in Cell Migration
E. von Hoerschelmann, C.C.M. Neumann, M. Felsenstein, J. Gogolok, A. Reutzel-Selke, I.M. Sauer, J. Pratschke, M. Bahra, R.B, Schmuck

Back

Perioperative Risk Assessment in Pancreatic Surgery Using Machine Learning
B. Pfitzner, J. Chromik, R. Brabender, E. Fischer, A. Kromer, A. Winter, S. Moosburner, I.M. Sauer, T. Malinka, J. Pratschke, B. Arnrich, M.M. Maurer

Back

A Note on Neurosurgical Resection and Why We Need to Rethink Cutting
T. Picht, M.L. Calvé, R. Tomasello, L. Fekonja, M.F. Gholami, M. Bruhn, C. Zwick, J.P. Rabe, C. Müller-Birn, P. Vajkoczy, I.M. Sauer, S. Zachow, J.A. Nyakatura, P. Ribault, F. Pulvermüller

Back

Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich

Back

Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien

Back

2020

Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model
H. Everwien, E. Keshi, K.H. Hillebrandt, B. Ludwig, M. Weinhart, P. Tang , A.S. Beierle, H. Napierala, J.M. Gassner, N. Seiffert, S. Moosburner, D. Geisel, A. Reutzel-Selke, B. Strücker, J. Pratschke, N. Haep, I.M. Sauer

Back

The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

Back

Dual versus single vessel normothermic ex vivo perfusion of rat liver grafts using metamizole for vasodilatation
F. Claussen, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, M. Nösser, P. Tang, L. Wegener, J. Pohl, A. Reutzel-Selke, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok

Back

Increased Cell-Free DNA Plasma Concentration Following Liver Transplantation Is Linked to Portal Hepatitis and Inferior Survival
F. Krenzien, S. Katou, A. Papa, B. Sinn, C. Benzing, L. Feldbrügge, C. Kamali, P. Brunnbauer, K. Splith, R.R. Lorenz, P. Ritschl, L. Wiering, R. Öllinger, W. Schöning, J. Pratschke, M. Schmelzle

Back

The Effects of MELD-Based Liver Allocation on Patient Survival and Waiting List Mortality in a Country with a Low Donation Rate
P.V. Ritschl, L. Wiering, T. Dziodzio, M. Jara, J. Kruppa, U. Schoeneberg, N. Raschzok, F. Butz, B. Globke, P. Seika, M. Maurer, M. Biebl, W. Schöning, M. Schmelzle, I.M. Sauer, F. Tacke, R. Öllinger, J. Pratschke

Back

Tissue-based miRNA mapping in alcoholic liver cirrhosis: different profiles in cirrhosis with or without hepatocellular carcinoma
P. Felgendreff, N. Raschzok, K. Kunze, A. Leder, S. Lippert, S. Klunk, H.M. Tautenhahn, H.M. Hau, R.B. Schmuck, A. Reutzel-Selke, I.M. Sauer, M. Bartels, M.H. Morgül

Back

Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner
S. Kuhn, K. Splith, C. Ballschuh, L. Feldbrügge, F. Krenzien, G. Atanasov, C. Benzing, H.M. Hau, C. Engelmann, T. Berg, J. Schulte Am Esch, J. Pratschke, S.C. Robson, M. Schmelzle

Back

This website or its third-party tools use cookies, which are necessary to its functioning and required to achieve the purpose illustrated in the Disclaimer. By closing this banner, scrolling this page, clicking a link or continuing to browse otherwise, you agree to the use of cookies.