Selected Publications
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.

2023

Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering  
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

Biomaterials Advances 2023, in print

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Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok

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Bioactive photocrosslinkable resin solely based on refined decellularized small intestine submucosa for vat photopolymerization of in vitro tissue mimics
L. Elomaa, L. Gerbeth, A. Almalla, N. Fribiczer, A. Daneshgar, P. Tang, K. Hillebrandt, S. Seiffert, I.M. Sauer, B. Siegmund, M. Weinhart

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Effect of pre-operative chemotherapy on the isolation outcome of primary human hepatocytes
M. Rissel, J. Pohl, S. Moosburner, J. Gaßner, R. Horner, K. Hillebrandt, D. Modest, J. Pratschke, I.M. Sauer, N. Raschzok

Tissue Engineering, Part C, 2023, in press

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2022

Inhibition of Vascular Endothelial Growth Factor Protects against the Development of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Wild-Type but Not in CD39-Null Mice
S. Knitter, G. Duwe, A.S. Beierle, S. Pesthy, P.V. Ritschl, K.H. Hillebrandt, A. Arnold, T. Malinka, D.P. Modest, M. Bahra, J. Pratschke, I.M. Sauer, M. Schmelzle, A. Andreou

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Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues
J. Snellings, E. Keshi, P. Tang, A. Daneshgar, E.C. Willma, L. Haderer, O. Klein, F. Krenzien, Th. Malink, P. Asbach, J. Pratschke, I.M. Sauer, J. Braun, I. Sack, K. Hillebrandt

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Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N

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Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas

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VolumetricOR: A new Approach to Simulate Surgical Interventions in Virtual Reality for Training and Education
M. Queisner, M. Pogorzhelskiy, Ch. Remde, J. Pratschke, I.M. Sauer

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Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?
M. Felsenstein, F. Lindhammer, M. Feist, K.H. Hillebrandt, L. Timmermann, C. Benzing, B. Globke, D. Zocholl, M. Hu, U. Fehrenbach, B.V. Sinn, U. Pelzer, I.M. Sauer, J. Pratschke, T. Malinka

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Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing
J.M. Alves, S. Prado-López, L. Tomás, M. Valecha, N. Estévez-Gómez, P. Alvariño, D. Geisel, D.P. Modest, I.M. Sauer, J. Pratschke, N. Raschzok, C. Sers, S. Mamlouk, D. Posada

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Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok

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Prognostic and Predictive Molecular Markers in Cholangiocarcinoma
S. Pavicevic, S. Reichelt, D. Uluk, I. Lurje, C. Engelmann, D.P. Modest, U. Pelzer, F. Krenzien, N. Raschzok, C. Benzing, I.M. Sauer, S. Stintzing, F. Tacke, W. Schöning, M. Schmelzle, J. Pratschke, G. Lurje

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FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer
N. Raschzok, S. Stintzing, V. Heinemann, G. Rauch, J. Ricke, M. Guckenberger, A. Kurreck, A.H.S. Alig, A. Stahler, L. Bullinger, M. Schmelzle, W. Schöning, G. Lurje, F. Krenzien, O. Haase, B. Rau, B. Gebauer, I.M. Sauer, J. Pratschke, D.P. Modest DP

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Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N

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[Digital documentation of complications in visceral surgery: possibilities and evaluation of an instrument for quality management]
A. Winter, M.M. Maurer, M. Schmelzle, T. Malinka, M. Biebl, P. Fikatas, D. Kröll, I.M. Sauer, M. Hippler-Benscheidt, J, Pratschke, S. Chopra

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Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
E. Keshi, P. Tang, M. Weinhart, H. Everwien, S. Moosburner, N. Seiffert, M. Lommel, U. Kertzscher, B. Globke, A. Reuztel-Selke, B. Strücker, J. Pratschke, I.M. Sauer, N. Haep, K.H. Hillebrandt

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Cancer Associated Fibroblasts Derived from Pancreatic Adenocarcinoma and Their Role in Cell Migration
E. von Hoerschelmann, C.C.M. Neumann, M. Felsenstein, J. Gogolok, A. Reutzel-Selke, I.M. Sauer, J. Pratschke, M. Bahra, R.B, Schmuck

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A Note on Neurosurgical Resection and Why We Need to Rethink Cutting
T. Picht, M.L. Calvé, R. Tomasello, L. Fekonja, M.F. Gholami, M. Bruhn, C. Zwick, J.P. Rabe, C. Müller-Birn, P. Vajkoczy, I.M. Sauer, S. Zachow, J.A. Nyakatura, P. Ribault, F. Pulvermüller

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Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich

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Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien

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2020

Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model
H. Everwien, E. Keshi, K.H. Hillebrandt, B. Ludwig, M. Weinhart, P. Tang , A.S. Beierle, H. Napierala, J.M. Gassner, N. Seiffert, S. Moosburner, D. Geisel, A. Reutzel-Selke, B. Strücker, J. Pratschke, N. Haep, I.M. Sauer

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The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

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Dual versus single vessel normothermic ex vivo perfusion of rat liver grafts using metamizole for vasodilatation
F. Claussen, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, M. Nösser, P. Tang, L. Wegener, J. Pohl, A. Reutzel-Selke, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok

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Increased Cell-Free DNA Plasma Concentration Following Liver Transplantation Is Linked to Portal Hepatitis and Inferior Survival
F. Krenzien, S. Katou, A. Papa, B. Sinn, C. Benzing, L. Feldbrügge, C. Kamali, P. Brunnbauer, K. Splith, R.R. Lorenz, P. Ritschl, L. Wiering, R. Öllinger, W. Schöning, J. Pratschke, M. Schmelzle

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The Effects of MELD-Based Liver Allocation on Patient Survival and Waiting List Mortality in a Country with a Low Donation Rate
P.V. Ritschl, L. Wiering, T. Dziodzio, M. Jara, J. Kruppa, U. Schoeneberg, N. Raschzok, F. Butz, B. Globke, P. Seika, M. Maurer, M. Biebl, W. Schöning, M. Schmelzle, I.M. Sauer, F. Tacke, R. Öllinger, J. Pratschke

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Tissue-based miRNA mapping in alcoholic liver cirrhosis: different profiles in cirrhosis with or without hepatocellular carcinoma
P. Felgendreff, N. Raschzok, K. Kunze, A. Leder, S. Lippert, S. Klunk, H.M. Tautenhahn, H.M. Hau, R.B. Schmuck, A. Reutzel-Selke, I.M. Sauer, M. Bartels, M.H. Morgül

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Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner
S. Kuhn, K. Splith, C. Ballschuh, L. Feldbrügge, F. Krenzien, G. Atanasov, C. Benzing, H.M. Hau, C. Engelmann, T. Berg, J. Schulte Am Esch, J. Pratschke, S.C. Robson, M. Schmelzle

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© 2023 Univ.-Prof. Dr. Igor M. Sauer | Charité – Universitätsmedizin Berlin | Disclaimer

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